Results 81 to 90 of about 9,606,964 (338)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Dossier: Mapping Screen Heritage (Introduction)
Archives of film and media are being challenged, critiqued, and reimagined. The heritage that has been preserved and the knowledge production to which it contributes has typically reinforced systemic structural barriers and inequalities and privileged ...
Rinella Cere +2 more
doaj +1 more source
Centerscope, formerly Scope, was published by the Boston University Medical Center "to communicate the concern of the Medical Center for the development and maintenance of improved health care in contemporary society.
Black, Paul H.
core +1 more source
Reducing regression test size by exclusion. [PDF]
Operational software is constantly evolving. Regression testing is used to identify the unintended consequences of evolutionary changes. As most changes affect only a small proportion of the system, the challenge is to ensure that the regression test set
Gallagher, K. +5 more
core +4 more sources
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Raman spectroscopy of cements: Problems and possibilities
Until recently there has been a common held misconception that Raman spectroscopy of cements is not possible, or at least so inconvenient as to make it impracticable.
Black, L
core
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Background Left ventricular hypertrophy (LVH) is associated with an increased risk for cardiovascular disease (CVD) events and all‐cause mortality. Many individuals without LVH have a left ventricular mass that exceeds the level predicted by their sex ...
D. Edmund Anstey +8 more
doaj +1 more source
Arbitration Of Investors’ Claims Against Issuers: An Idea Whose Time Has Come? [PDF]
Ever since the U.S. Supreme Court held that arbitration provisions contained in brokerage customers’ agreements were enforceable with respect to federal securities claims, proposals have been floated to include in an issuer’s governance documents a ...
Black, Barbara
core +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source

