Results 61 to 70 of about 14,429,121 (287)
Black Market International Artist Statement [PDF]
Artist statement for Black Market International artist collective.
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The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Coarse-graining black holes out of equilibrium with boundary observables on time slice
In black hole thermodynamics, defining coarse-grained entropy for dynamical black holes has long been a challenge, and various proposals, such as generalized entropy, have been explored.
Daichi Takeda
doaj +1 more source
The amphipod Dikerogammarus villosus has colonized most of the European main inland water bodies in less than 20 years, having deteriorating effect on the local benthic communities. Our aim was to reveal the species phylogeography in the native Black Sea
Tomasz Rewicz +4 more
doaj +1 more source
Report of accomplishment, Emergency Flood Restoration Project, Black Hills National Forest
"Report of accomplishment, Emergency Flood Restoration Project, under Section 216 Flood Control Act of 1950 - PL 534, Eastern Flank - Black Hills National Forest." Prepared by Black Hills National Forest staff.
Black Hills National Forest (Agency : U.S.)
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Black Market International Cover Page [PDF]
Cover page for the Black Market International submission package.
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Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Black Elk Peak Lookout Tower view looking out windows
In folder: "Harney Peak (Black Elk Peak) Lookout Tower and other structures.
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