Results 101 to 110 of about 1,420,693 (238)
Accounting for the great divergence [PDF]
, 2013 This paper “accounts” for the Great Divergence between Europe and Asia in two ways. In the sense of measurement: (1) the traditional view, in which the Great Divergence had late medieval origins and was already well under way during the early modern ...
Broadberry, S. N.
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Concept of the international programs monitoring the transboundary transport of pollution in the Black sea [PDF]
, 2013 The shelf of Black sea is rich to the lid posits of oil. The estimation of the reserves of the hydrocarbons only of western part of the Ukrainian shelf composes of 3,5 trln.
Degtyarev, Vladimir P. +2 more
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Some considerations on the EU Danube Strategy and the Black Sea Region [PDF]
The Danube strategy can only constitute a step forward regarding the stated intentions, via the Black Sea Synergy program of the European Union towards the boosting of economic development, democratic governance, security etc., in the Black Sea region ...
Costel COROBAN
core
Breeding Lesser Black-backed Gulls Larus graellsii and Herring Gulls Larus argentatus: coexistence or competition? [PDF]
, 1999 While Lesser Black-backed Gull Larus graellsii numbers increase substantially at the German North Sea coast since the late 1980s, Herring Gull Larus argentatus numbers have been roughly stable since the mid-1980s.
Freyer, T. +3 more
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Role of visceral adiposity in functional recovery after myocardial infarction in females
Journal of Education, Health and SportTitle: Visceral Adiposity and Functional Recovery After Myocardial Infarction in Obese Female Patients: A Prospective Cohort Study Background: Visceral adiposity is increasingly recognized as a critical determinant of myocardial infarction (MI ...
Yu. Zhukova, M. Zak
doaj +1 more source