Results 61 to 70 of about 3,603 (219)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Book Review: Slavoj Žižek, Against the Double Blackmail
Forum, 2016 Of interest to few beyond the fellow specialist and often uncritically aligning with harmful clichés, the new book on Europe’s refugee crisis by the radical Slovenian philosopher Slavoj Žižek ultimately fails in its attempt to emulate the proud tradition
Cain Shelley
doaj +3 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
A CLINICAL CASE OF ACTUALIZATION OF SUICIDAL BEHAVIOR IN SELFISOLATION IN COVID – 19
Актуальные проблемы теоретической и клинической медицины, 2022 In the article the clinical case of suicidal behavior is presented on the type of demonstratively-blackmail protest in the conditions of self-isolation at COVID - 19.
A. Y. Tolstikova
doaj
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Sextortion on the Internet: reactions of minors and their vulnerability
Психология и правоContext and relevance. The involvement of children and adolescents in sexual Internet communications has become one of the most significant childhood problems for legal psychology.
A.S. Medvedeva
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Predicting Mother Abuse Based on Spouse\'s Emotional Blackmail and Self-Esteem [PDF]
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i ĪlāmIntroduction: Domestic violence, including child, parent, and spousal abuse, is a growing global issue, particularly affecting teenage mothers due to its detrimental effects on the family system.
Zabihollah Abbaspour +1 more
doaj
Coercion, Fraud, and What is Wrong With Blackmail [PDF]
, 2016 Several theorists argue that blackmail is morally wrong because the blackmail proposal is coercive. These coercion-based views are promising but incomplete.
Stephen Galoob, Galoob, Stephen
core +1 more source