Results 81 to 90 of about 3,603 (219)
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Blackmail: The Paradigmatic Crime [PDF]
, 1993 The ongoing debate about the rationale for punishing blackmail assumes that there is something odd about the crime. Why, the question goes, should demanding money to conceal embarrassing information be criminalized when there is nothing wrong with the ...
Fletcher, George P.
core +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Strangers No More: the Initial Hitchcock murder
CINEJ Cinema Journal, 2011 This article analyzes the various levels of violence and graphic detail in the initial Hitchcock murder scenes. Through a detailed close reading of these scenes from Blackmail, Strangers on a Train, and Frenzy, I expose the different and increasing ...
Vlad Dima
doaj +1 more source
Testing Competing Theories: Blackmail
, 2013 This chapter examines the offense of blackmail. It first summarizes the competing theories of blackmail: theories of blackmail as a crime against the threat recipient, as a crime against third parties, as a societal harm, and as non-crime.
Paul H. Robinson, Robinson, Paul
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
UNELE PRECIZĂRI PRIVIND ACCEPŢIUNILE JURIDICE ŞI EXTRAJURIDICE ALE CONCEPTULUI DE ŞANTAJ
Studia Universitatis Moldaviae: Stiinte Sociale, 2007 The author analyzes some explanations regarding the juridical and extra juridical acceptations of the blackmail concept. After a thorough analysis, the author comes to the conclusion that the notion of racket does not have to outrun the domain of ...
USM ADMIN
doaj
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source