Results 71 to 80 of about 3,603 (219)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Revista Chilena de Derecho, 2008 La reciente sentencia que condenó a dos de los acusados por el delito de amenazas en contra del Conservador de Bienes Raíces de Santiago, es una buena oportunidad para referirse a una de las hipótesis delictivas más complejas del ámbito penal, cuya ...
Álvaro Fernández Díaz
doaj
REVIEW: Harrowing story of prejudice and religious blackmail
Pacific Journalism Review, 2015 Craddock, Pat (2015). Harrowing story of prejudice and religious blackmail. Pacific Journalism Review, 21(2): 208-210. Review of Murder That Wasn’t. The Case of George Gwaze, by Felicity Goodyear-Smith. Dunedin: Otago University Press, 2015. 180pp.
Patrick Craddock
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
, 2011 Despite the fact that blackmail constitutes a voluntary transaction between two parties, it is deemed to be a criminal offence in most legal systems. Traditional economic approach to this so-called ‘paradox of blackmail’ emphasizes welfare loss generated
Oleg Yerokhin (19584427)
core +4 more sources
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Sfera Politicii, 2012 This research is based on the hypothesis that in Romania the consolidation of democracy was undermined not only at the beginning (path-dependency theory), but also at its end, in the last years.
Dan Pavel
doaj
The economy of social blackmail as a system of moral regulation of consumption in Ukrainian society in the context of the war [PDF]
СоціологіяThе article is devoted to theoretical analysis and conceptualisation of the ‘economy of social blackmail’ — a specific form of moral regulation of consumption that has taken root in Ukrainian society amidst a full-scale armed invasion.
Marharyta Shyrokova, Oleg Mazuryk
doaj +1 more source