Results 91 to 100 of about 5,263,232 (399)

Focus on bladder cancer [PDF]

Cancer Cell, 2004
Supported by NIH Specialized Programs of Research Excellence Grant in Genitourinary Cancer CA91846, and National Cancer Institute Grants CA16672, CA066723, and CA85078.
Anita L. Sabichi, Bogdan Czerniak, Arlene O. Siefker-Radtke, Colin P.N. Dinney, Xifeng Wu, David J. McConkey, Liana Adam, H. Barton Grossman, Randall E. Millikan, Ashish M. Kamat, William F. Benedict, Tomasz Tuziak, Menashe Bar-Eli   +12 more
openaire   +3 more sources

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Neutrophil-to-lymphocyte ratio as a bladder cancer biomarker: assessing prognostic and predictive value in SWOG 8710 [PDF]

, 2017
No abstract ...
Advanced Bladder Cancer (ABC) Meta-analysis Collaboration, Asano, Ferro, Gondo, Grenader, Guthrie, Krane, Linton, Lorente, Mitchell, Ojerholm, Templeton, Viers   +12 more
core   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Supplementation of Probiotic Butyricicoccus pullicaecorum Mediates Anticancer Effect on Bladder Urothelial Cells by Regulating Butyrate-Responsive Molecular Signatures

Diagnostics, 2021
In bladder cancer, urothelial carcinoma is the most common histologic subtype, accounting for more than 90% of cases. Pathogenic effects due to the dysbiosis of gut microbiota are localized not only in the colon, but also in regulating bladder cancer ...
Yen-Chieh Wang, Wei-Chi Ku, Chih-Yi Liu, Yu-Che Cheng, Chih-Cheng Chien, Kang-Wei Chang, Chi-Jung Huang   +6 more
doaj   +1 more source

Attenuated XPC expression is not associated with impaired DNA repair in bladder cancer [PDF]

, 2015
Bladder cancer has a high incidence with significant morbidity and mortality. Attenuated expression of the DNA damage response protein Xeroderma Pigmentosum complementation group C (XPC) has been described in bladder cancer.
Boormans, J.L. (Joost), Brandsma, I. (Inger), Bruens, S.T. (Serena), Gent, D.C. (Dik) van, Hoeijmakers, J.H.J. (Jan), Jaspers, N.G.J. (Nicolaas), Kanaar, R. (Roland), Leenders, G.J.H.L. (Geert), Naipal, K.A.T. (Kishan A.T.), Pothof, J. (Joris), Raams, A. (Anja), Verkaik, N.S. (Nicole)   +11 more
core   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Detection of genome-wide methylation changes in bladder cancer by long-read sequencing of urinary DNA

Clinical Epigenetics
Background Non-invasive urine tests for bladder cancer (BC) could reduce dependence on flexible cystoscopy for diagnosis and surveillance. Most recent developments in urine testing are based on targeted detection of genomic and/or epigenomic markers.
Anshita Goel, Benjamin J. Tura, Joanne D. Stockton, Nicholas Tovey, Luke Ames, Andrew D. Beggs, Maurice P. Zeegers, Nicholas D. James, K. K. Cheng, Richard T. Bryan, Douglas G. Ward, Roland Arnold   +11 more
doaj   +1 more source

Genetic variation in Glutathione S-Transferase Omega-1, Arsenic Methyltransferase and Methylene-tetrahydrofolate Reductase, arsenic exposure and bladder cancer: a case–control study [PDF]

, 2012
Background Ingestion of groundwater with high concentrations of inorganic arsenic has been linked to adverse health outcomes, including bladder cancer, however studies have not consistently observed any elevation in risk at lower concentrations.
Beebe-Dimmer, Jennifer L, Cooney, Kathleen A, Iyer, Priyanka T, Keele, Greg R, Lange, Ethan M, Mehta, Shilpin, Meliker, Jaymie R, Nriagu, Jerome O, Schottenfeld, David, Schwartz, Ann G, Zuhlke, Kimberly A   +10 more
core   +3 more sources

USP24-GSDMB complex promotes bladder cancer proliferation via activation of the STAT3 pathway

International Journal on Biological Sciences, 2020
Background: Bladder cancer is the fourth and tenth most common malignancy in men and women worldwide, respectively. One of the main reasons for the unsatisfactory therapeutic control of bladder cancer is that the molecular biological mechanism of bladder
Haiqing He, Bin Zhang, B. Yan, M. Xiao, Jiannan Ren, Dong Zi, Liang Zhu, Zhao-hui Zhong, Xiaokun Zhao, Xin Jin, Weiyan Xiong   +10 more
semanticscholar   +1 more source