Results 11 to 20 of about 321,570 (322)

Immunohistochemistry as a paramount tool in research of normal urothelium, bladder cancer and bladder pain syndrome

European Journal of Histochemistry, 2021
The urothelium, an epithelium of the urinary bladder, primarily functions as blood-urine permeability barrier. The urothelium has a very slow turn-over under normal conditions but is capable of extremely fast response to injury.
Daša Zupančič, Rok Romih
doaj   +1 more source

Beyond the urothelium: Interplay between autonomic nervous system and bladder inflammation in urinary tract infection, bladder pain syndrome with interstitial cystitis and neurogenic lower urinary tract dysfunction in spinal cord injury—ICI‐RS 2023

Neurourology and Urodynamics, 2023
Inflammation and neuronal hypersensitivity are reactive protective mechanisms after urothelial injury. In lower urinary tract dysfunctions (LUTD), such as urinary tract infection (UTI), bladder pain syndrome with interstitial cystitis (BPS/IC) and ...
Michel I A Wyndaele, A. Charrua, F. Hervé, P. Aronsson, Luke Grundy, Vik Khullar, A. Wein, P. Abrams, Francisco Cruz, C. Cruz   +9 more
semanticscholar   +1 more source

Animal models of interstitial cystitis/bladder pain syndrome

Frontiers in Physiology, 2023
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic disorder characterized by pelvic and/or bladder pain, along with lower urinary tract symptoms that have a significant impact on an individual’s quality of life.
Cindy Tay, Luke Grundy
semanticscholar   +1 more source

Glycosaminoglycan Replacement Therapy with Intravesical Instillations of Combined Hyaluronic Acid and Chondroitin Sulfate in Patients with Recurrent Cystitis, Post-radiation Cystitis and Bladder Pain Syndrome: A Narrative Review

Pain and Therapy, 2023
Defects in the glycosaminoglycan layer (GAG) of the bladder mucosa have been identified as a significant contributor to the pathogenesis and clinical progression of chronic inflammatory diseases of the bladder, such as post-radiation cystitis, bladder ...
S. Poletajew, Magdalena M Brzózka, Wojciech Krajewski, H. Kamecki, Łukasz Nyk, P. Kryst   +5 more
semanticscholar   +1 more source

Usefulness of Urinary Biomarkers for Assessing Bladder Condition and Histopathology in Patients with Interstitial Cystitis/Bladder Pain Syndrome

International Journal of Molecular Sciences, 2022
This study investigated the usefulness of urinary biomarkers for assessing bladder condition and histopathology in patients with interstitial cystitis/bladder pain syndrome (IC/BPS).
Yuan-Hong Jiang, J. Jhang, Y. Hsu, H. Kuo   +3 more
semanticscholar   +1 more source

Pathomechanism of Interstitial Cystitis/Bladder Pain Syndrome and Mapping the Heterogeneity of Disease [PDF]

International Neurourology Journal, 2016
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a heterogeneous syndrome which is usually characterized by urinary frequency, nocturia, and bladder pain.
Jia-Fong Jhang, Hann-Chorng Kuo
doaj   +1 more source

Multimodal Single‐Cell Analyses Outline the Immune Microenvironment and Therapeutic Effectors of Interstitial Cystitis/Bladder Pain Syndrome

Advancement of science, 2022
Interstitial cystitis/bladder pain syndrome (IC/BPS) has a significant impact on quality of life, but the etiopathogenesis remains largely unknown. The bladder microenvironment of patients with IC/BPS to obtain biological evidence supporting diagnosis ...
Fei Su, Wei Zhang, L. Meng, Wei Zhang, Xiaodong Liu, Xiaorui Liu, Meng Chen, Yaoguang Zhang, Fei Xiao   +8 more
semanticscholar   +1 more source

Bladder Pain Syndrome: A Review

European Medical Journal Urology, 2020
Therapy of bladder pain syndrome (BPS) presents a significant challenge in clinical practice. Over the last 20 years, there have been important efforts directed at understanding the syndrome’s aetiology and therapeutic challenges.
Gokhan Calik, Jean de la Rosett
doaj   +1 more source

The use of botulinum toxin (BoNT) in urology - review

Journal of Education, Health and Sport, 2022
Introduction and purpose Botulinum neurotoxin (BoNT) prevents the release of acetylcholine into the synaptic cleft of the neuromuscular junction, which causes flaccid muscle paralysis.
Jakub Szwed, Monika Szwed, Weronika Szwed, Nadia Miga   +3 more
doaj   +1 more source

Current Understanding of the Pathophysiology and Novel Treatments of Interstitial Cystitis/Bladder Pain Syndrome

Biomedicines, 2022
The pathophysiology of interstitial cystitis/bladder pain syndrome (IC/BPS) is multifactorial. Identifying the clinical characteristics and cystoscopic findings of bladder-centered IC/BPS facilitates optimal treatment strategies targeting the diseased ...
J. Jhang, Yuan-Hong Jiang, H. Kuo
semanticscholar   +1 more source