Results 11 to 20 of about 297,968 (336)

Beyond the urothelium: Interplay between autonomic nervous system and bladder inflammation in urinary tract infection, bladder pain syndrome with interstitial cystitis and neurogenic lower urinary tract dysfunction in spinal cord injury—ICI‐RS 2023

Neurourology and Urodynamics, 2023
Inflammation and neuronal hypersensitivity are reactive protective mechanisms after urothelial injury. In lower urinary tract dysfunctions (LUTD), such as urinary tract infection (UTI), bladder pain syndrome with interstitial cystitis (BPS/IC) and ...
Michel I A Wyndaele, A. Charrua, F. Hervé, P. Aronsson, Luke Grundy, Vik Khullar, Alan J Wein, P. Abrams, Francisco Cruz, C. Cruz   +9 more
semanticscholar   +1 more source

Animal models of interstitial cystitis/bladder pain syndrome

Frontiers in Physiology, 2023
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic disorder characterized by pelvic and/or bladder pain, along with lower urinary tract symptoms that have a significant impact on an individual’s quality of life.
Cindy Tay, Luke Grundy
semanticscholar   +1 more source

Use of Urinary Biomarkers in Discriminating Interstitial Cystitis/Bladder Pain Syndrome from Male Lower Urinary Tract Dysfunctions

International Journal of Molecular Sciences, 2023
To analyze the urinary biomarkers in men with lower urinary-tract symptoms (LUTS) and identify interstitial cystitis/bladder pain syndrome (IC/BPS) from the other lower urinary-tract dysfunctions (LUTDs) by the levels of characteristic urinary biomarkers.
Wan-Ru Yu, Yuan-Hong Jiang, J. Jhang, H. Kuo   +3 more
semanticscholar   +1 more source

Glycosaminoglycan Replacement Therapy with Intravesical Instillations of Combined Hyaluronic Acid and Chondroitin Sulfate in Patients with Recurrent Cystitis, Post-radiation Cystitis and Bladder Pain Syndrome: A Narrative Review

Pain and Therapy, 2023
Defects in the glycosaminoglycan layer (GAG) of the bladder mucosa have been identified as a significant contributor to the pathogenesis and clinical progression of chronic inflammatory diseases of the bladder, such as post-radiation cystitis, bladder ...
S. Poletajew, Magdalena M Brzózka, Wojciech Krajewski, H. Kamecki, Łukasz Nyk, P. Kryst   +5 more
semanticscholar   +1 more source

Botulinum Toxin Therapy for Bladder Pain Syndrome/Interstitial Cystitis

Current Bladder Dysfunction Reports, 2023
Purpose of Review Bladder pain syndrome (BPS)/interstitial cystitis (IC) can also be classified as either non-ulcerative or ulcerative, corresponding to the characteristic cystoscopic findings under hydrodistention.
M. Rahnama’i, Aida Javan Balegh Marand, D. Janssen, H. Mostafaei, Sotirios Gatsos, S. Hajebrahimi, A. Apostolidis, R. Taneja   +7 more
semanticscholar   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Current Understanding of the Pathophysiology and Novel Treatments of Interstitial Cystitis/Bladder Pain Syndrome

Biomedicines, 2022
The pathophysiology of interstitial cystitis/bladder pain syndrome (IC/BPS) is multifactorial. Identifying the clinical characteristics and cystoscopic findings of bladder-centered IC/BPS facilitates optimal treatment strategies targeting the diseased ...
J. Jhang, Yuan-Hong Jiang, H. Kuo
semanticscholar   +1 more source

Central amygdala metabotropic glutamate receptor 5 in the modulation of visceral pain [PDF]

, 2012
Painful bladder syndrome is a debilitating condition that affects 3–6% of women in the United States. Multiple lines of evidence suggest that changes in central nervous system processing are key to the development of chronic bladder pain conditions, but ...
Bruchas, Michael R, Crock, Lara W, Gereau, Robert W, IV, Kolber, Benedict J, Morgan, Clinton D, Sadler, Katelyn E, Vogt, Sherri K   +6 more
core   +2 more sources

Usefulness of Urinary Biomarkers for Assessing Bladder Condition and Histopathology in Patients with Interstitial Cystitis/Bladder Pain Syndrome

International Journal of Molecular Sciences, 2022
This study investigated the usefulness of urinary biomarkers for assessing bladder condition and histopathology in patients with interstitial cystitis/bladder pain syndrome (IC/BPS).
Yuan-Hong Jiang, J. Jhang, Y. Hsu, H. Kuo   +3 more
semanticscholar   +1 more source

Multimodal Single‐Cell Analyses Outline the Immune Microenvironment and Therapeutic Effectors of Interstitial Cystitis/Bladder Pain Syndrome

Advancement of science, 2022
Interstitial cystitis/bladder pain syndrome (IC/BPS) has a significant impact on quality of life, but the etiopathogenesis remains largely unknown. The bladder microenvironment of patients with IC/BPS to obtain biological evidence supporting diagnosis ...
Fei Su, Wei Zhang, L. Meng, Wei Zhang, Xiaodong Liu, Xiaorui Liu, Meng Chen, Yaoguang Zhang, Fei Xiao   +8 more
semanticscholar   +1 more source