Results 21 to 30 of about 281,092 (320)

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

The use of botulinum toxin (BoNT) in urology - review

open access: yesJournal of Education, Health and Sport, 2022
Introduction and purpose Botulinum neurotoxin (BoNT) prevents the release of acetylcholine into the synaptic cleft of the neuromuscular junction, which causes flaccid muscle paralysis.
Jakub Szwed   +3 more
doaj   +1 more source

Multimodal Single‐Cell Analyses Outline the Immune Microenvironment and Therapeutic Effectors of Interstitial Cystitis/Bladder Pain Syndrome

open access: yesAdvancement of science, 2022
Interstitial cystitis/bladder pain syndrome (IC/BPS) has a significant impact on quality of life, but the etiopathogenesis remains largely unknown. The bladder microenvironment of patients with IC/BPS to obtain biological evidence supporting diagnosis ...
Fei Su   +8 more
semanticscholar   +1 more source

Usefulness of Urinary Biomarkers for Assessing Bladder Condition and Histopathology in Patients with Interstitial Cystitis/Bladder Pain Syndrome

open access: yesInternational Journal of Molecular Sciences, 2022
This study investigated the usefulness of urinary biomarkers for assessing bladder condition and histopathology in patients with interstitial cystitis/bladder pain syndrome (IC/BPS).
Yuan-Hong Jiang   +3 more
semanticscholar   +1 more source

Intravesical Injection of Abobotulinumtoxin-A in Patients with Bladder Pain Syndrome/Interstitial Cystitis

open access: yesUrology Research and Practice, 2023
Objective: This study aimed to evaluate retrospectively the outcomes of Abobotulinumtoxin-A (Dysport®) intravesical injection in refractory interstitial cystitis/ bladder pain syndrome patients to first- and second-line treatment.
Mohammad-Sajjad Rahnamai   +4 more
doaj   +1 more source

Current Understanding of the Pathophysiology and Novel Treatments of Interstitial Cystitis/Bladder Pain Syndrome

open access: yesBiomedicines, 2022
The pathophysiology of interstitial cystitis/bladder pain syndrome (IC/BPS) is multifactorial. Identifying the clinical characteristics and cystoscopic findings of bladder-centered IC/BPS facilitates optimal treatment strategies targeting the diseased ...
J. Jhang, Yuan-Hong Jiang, H. Kuo
semanticscholar   +1 more source

Immunomodulation—A Molecular Solution to Treating Patients with Severe Bladder Pain Syndrome?

open access: yesEuropean Urology Open Science, 2021
Background: Patients with bladder pain syndrome experience debilitating pain and extreme frequency of urination. Numerous therapeutic approaches have been tested, but as the molecular basis of disease has remained unclear, specific therapies are not ...
Björn Wullt   +5 more
doaj   +1 more source

Broaden Horizons: The Advancement of Interstitial Cystitis/Bladder Pain Syndrome

open access: yesInternational Journal of Molecular Sciences, 2022
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a debilitating disease that induces mental stress, lower urinary symptoms, and pelvic pain, therefore resulting in a decline in quality of life.
Jin Li, Xianyanling Yi, J. Ai
semanticscholar   +1 more source

Bladder Pain Syndrome Treated with Triple Therapy with Gabapentin, Amitriptyline, and a Nonsteroidal Anti-Inflammatory Drug [PDF]

open access: yesInternational Neurourology Journal, 2010
PurposeBladder pain syndrome is a chronic disease that manifests as bladder pain, frequency, nocturia, and urgency. Gabapentin, amitriptyline, and nonsteroidal anti-inflammatory drugs are efficacious treatments for bladder pain syndrome.
Jea Whan Lee   +2 more
doaj   +1 more source

Immune cell profiles of patients with interstitial cystitis/bladder pain syndrome

open access: yesJournal of Translational Medicine, 2022
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a disorder characterized by bladder pain upon filling which severely affects quality of life. Clinical presentation can vary.
R. Moldwin   +13 more
semanticscholar   +1 more source

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