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Bladder pain syndrome is an important chronic pain syndrome which seriously reduces the patients’ quality of life. It is a diagnosis of exclusion. It is defined as a clinical diagnosis composed of chronic (>6 months) pain/pressure/discomfort that is ...
Taner Koçak +5 more
doaj +3 more sources
Botulinum Toxin A for Bladder Pain Syndrome/Interstitial Cystitis [PDF]
Botulinum neurotoxin A (BoNT-A), derived from Clostridium botulinum, has been used clinically for several diseases or syndrome including chronic migraine, spasticity, focal dystonia and other neuropathic pain. Chronic pelvic or bladder pain is the one of
Bin Chiu +3 more
doaj +3 more sources
Low-energy shock wave (LESW) therapy is known to facilitate tissue regeneration with analgesic and anti-inflammatory effects. LESW treatment has been demonstrated to be effective in treating chronic prostatitis and pelvic pain syndrome as well as ...
Yuan-Hong Jiang +3 more
doaj +2 more sources
The Expression of Inflammatory Mediators in Bladder Pain Syndrome [PDF]
Bladder pain syndrome (BPS) pathology is poorly understood. Treatment strategies are empirical, with limited efficacy, and affected patients have diminished quality of life.We examined the hypothesis that inflammatory mediators within the bladder contribute to BPS pathology.Fifteen women with BPS and 15 women with stress urinary incontinence without ...
Offiah, Ifeoma +12 more
core +9 more sources
The urothelium, an epithelium of the urinary bladder, primarily functions as blood-urine permeability barrier. The urothelium has a very slow turn-over under normal conditions but is capable of extremely fast response to injury.
Daša Zupančič, Rok Romih
doaj +1 more source
Inflammation and neuronal hypersensitivity are reactive protective mechanisms after urothelial injury. In lower urinary tract dysfunctions (LUTD), such as urinary tract infection (UTI), bladder pain syndrome with interstitial cystitis (BPS/IC) and ...
Michel I A Wyndaele +9 more
semanticscholar +1 more source
Animal models of interstitial cystitis/bladder pain syndrome
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic disorder characterized by pelvic and/or bladder pain, along with lower urinary tract symptoms that have a significant impact on an individual’s quality of life.
Cindy Tay, Luke Grundy
semanticscholar +1 more source
Noninvasive experimental bladder pain assessment in painful bladder syndrome [PDF]
ObjectiveTo compare bladder sensitivity between patients with pelvic pain and patients who were pain free, undergoing noninvasive, controlled bladder distension via diuresis. We also sought to measure potential mechanisms underlying bladder sensitivity.DesignProspective observational study.SettingCommunity teaching hospital.PopulationReproductive‐age ...
F F, Tu, J N, Kane, K M, Hellman
openaire +2 more sources
Defects in the glycosaminoglycan layer (GAG) of the bladder mucosa have been identified as a significant contributor to the pathogenesis and clinical progression of chronic inflammatory diseases of the bladder, such as post-radiation cystitis, bladder ...
S. Poletajew +5 more
semanticscholar +1 more source
Pathomechanism of Interstitial Cystitis/Bladder Pain Syndrome and Mapping the Heterogeneity of Disease [PDF]
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a heterogeneous syndrome which is usually characterized by urinary frequency, nocturia, and bladder pain.
Jia-Fong Jhang, Hann-Chorng Kuo
doaj +1 more source

