Results 51 to 60 of about 1,939,534 (289)

A comparison of two intravesical bladder instillations for interstitial cystitis/bladder pain syndrome

, 2021
Objective: Bladder pain syndrome (BPS) is a chronic pain condition associated with injury to the glycosoaminoglycan (GAG) layer. We aimed to prospectively evaluate iAluRil® with multi-centre tertiary urogynaecology collaboration.
Yin, J, Young, N, Goh, J, Lee, J, Keane, J, Hall, P, Moore, K, Rosamilia, A, Atherton, M, Higgs, P, Leitch, A   +10 more
core   +1 more source

Ilioinguinal and iliohypogastric neuralgia as an etiology of bladder pain syndrome

Urology Case Reports, 2020
Chronic neuropathic pain due to iliohypogastric (IH) or ilioinguinal (IL) nerve entrapment or injury may demonstrate as referred pain to the genito-urinary organs.
Dorota J. Hawksworth, A. Lee Dellon, Amin S. Herati   +2 more
doaj   +1 more source

Acid-sensing channels in human bladder: expression, function and alterations during bladder pain syndrome

, 2011
PURPOSE: We examined the possible role of H(+) activated acid-sensing ion channels in pain perception. We characterized expression in bladder dome biopsies from patients with bladder pain syndrome and controls, in cultured human urothelium and in ...
Kessler, T.M., Kellenberger, Stephan, Kessler, Thomas M, Fiona C. Burkhard, Monastyrskaya, K, Thomas M. Kessler, Sánchez-Freire, V., Maxime G. Blanchard, Burkhard, F.C., Kellenberger, S., Blanchard, M.G., Sánchez-Freire, V, Katia Monastyrskaya, Sánchez-Freire, Verónica, Kessler, T M, Monastyrskaya, K., Kellenberger, S, Monastyrskaya, Katia, Burkhard, F C, Verónica Sánchez-Freire, Blanchard, M G, Stephan Kellenberger, Blanchard, Maxime G, Burkhard, Fiona C   +23 more
core   +1 more source

Enhanced Anandamide Plasma Levels in Patients with Complex Regional Pain Syndrome following Traumatic Injury: A Preliminary Report [PDF]

, 2009
The complex regional pain syndrome (CRPS) is a disabling neuropathic pain condition that may develop following injuries of the extremities. The pathogenesis of this syndrome is not clear; however, it includes complex interactions between the nervous and ...
Schelling, G., Huge, V., Kaufmann, I., G. Schelling, Campolongo, P., Thiel, M., V. Huge, M. Vogeser, Vogeser, M., CAMPOLONGO, Patrizia, I. Kaufmann, Hauer, D., A. Chouker, M. Thiel, Chouker, A., D. Hauer   +15 more
core   +1 more source

Novel Treatment of Chronic Bladder Pain Syndrome and Other Pelvic Pain Disorders by OnabotulinumtoxinA Injection

Toxins, 2015
Chronic pelvic pain (CPP) is defined as pain in the pelvic organs and related structures of at least 6 months’ duration. The pathophysiology of CPP is uncertain, and its treatment presents challenges.
Jia-Fong Jhang, Hann-Chorng Kuo
doaj   +1 more source

The Expression of Inflammatory Mediators in Bladder Pain Syndrome [PDF]

European Urology, 2016
Bladder pain syndrome (BPS) pathology is poorly understood. Treatment strategies are empirical, with limited efficacy, and affected patients have diminished quality of life.We examined the hypothesis that inflammatory mediators within the bladder contribute to BPS pathology.Fifteen women with BPS and 15 women with stress urinary incontinence without ...
Offiah, Ifeoma, Didangelos, Athanasios, Dawes, John, Cartwright, Rufus, Khullar, Vik, Bradbury, Elizabeth J., O'Sullivan, Suzanne, Williams, Dic, Chessell, Iain P., Pallas, Kenny, Graham, Gerry, O’Reilly, Barry A., McMahon, Stephen B.   +12 more
openaire   +6 more sources

Circulating sex steroids and bladder pain sensitivity in dysmenorrhea

Molecular Pain, 2021
Although elevated estradiol levels facilitate chronic pelvic pain in animal models, it remains to be determined whether sex steroid levels are altered in a cross-section of women with chronic pelvic pain (CPP) and those at-risk for developing CPP.
Kevin M Hellman, Folabomi A Oladosu, Ellen F Garrison, Genevieve E Roth, Katlyn E Dillane, Frank F Tu   +5 more
doaj   +1 more source

A possible role of the locus coeruleus in complex regional pain syndrome [PDF]

, 2012
Heightened sensitivity to painful stimulation commonly spreads from the affected limb to the ipsilateral forehead in patients with complex regional pain syndrome (CRPS).
Peter D Drummond, Drummond, P.D., Peter D. Drummond   +2 more
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, EarlyView.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source