Results 141 to 150 of about 70,987 (344)

Ex vivo fluorescence confocal microscopy for assessment of ureteroscopic biopsy adequacy in upper tract urothelial carcinoma

BJU International, EarlyView.
Objectives To evaluate the feasibility of ex vivo fluorescence confocal microscopy (FCM) for real‐time assessment of ureteroscopic biopsy specimen adequacy in patients with suspected upper tract urothelial carcinoma (UTUC). Patients and Methods In this prospective, single‐centre feasibility study, four ureteroscopic biopsy specimens obtained from two ...
Karim Daher, Nicolas A. Soputro, Mohammad El Hussein, Salim K. Younis, Lin Wang, Abdulrahman Al‐Bayati, Rui Bernardino, Mohamad Watfa, Ruben Olivares, Nima Almassi, Christopher J. Weight, Zeyad R. Schwen, Jihad Kaouk, Jane K. Nguyen, Riccardo Autorino   +14 more
wiley   +1 more source

Transurethral thulium laser resection via ureterorenoscope for pediatric low-grade urothelial carcinoma of the bladder: a case report

BMC Surgery
Objective To report a case of pediatric bladder urothelial carcinoma treated with transurethral thulium laser resection and, based on a literature review, to discuss its clinical characteristics, diagnostic considerations, and surgical strategies adapted
Pinyao Liang, Jianheng Chen, Jian Shen, Yumin Wang, Junxiong Li, Jingbo Qin, Peng Gu, Xiaodong Liu   +7 more
doaj   +1 more source

XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies. [PDF]

, 2018
Treatment options for high grade urothelial cancers are limited and have remained largely unchanged for several decades. Selinexor (KPT-330), a first in class small molecule that inhibits the nuclear export protein XPO1, has shown efficacy as a single ...
Baek, Han Bit, Fernandez-Rubio, Aleida, Gandour-Edwards, Regina, Ghosh, Paramita M, Landesman, Yosef, Libertini, Stephen J, Lombard, Alan P, Mudryj, Maria, Nakagawa, Rachel, Nishida, Kristine, Siddiqui, Salma, Vidallo, Kathleen, Vinall, Ruth, Weiss, Robert H, Wettersten, Hiromi   +14 more
core   +1 more source

Long-Term Experience of Chemoradiotherapy Combined with Deep Regional Hyperthermia for Organ Preservation in High-Risk Bladder Cancer (Ta, Tis, T1, T2). [PDF]

, 2019
BackgroundThe aim of this study was to evaluate the efficacy and safety of chemoradiotherapy (RCT) combined with regional deep hyperthermia (RHT) of high-risk bladder cancer after transurethral resection of bladder tumor (TUR-BT).Materials and ...
Bertz, Simone, Fietkau, Rainer, Gall, Christine, Haderlein, Marlen, Hartmann, Arndt, Keck, Bastian, Kühn, Reinhard, Merten, Ricarda, Ott, Oliver, Rödel, Claus Michael, Uter, Wolfgang, Weiss, Christian, Wullich, Bernd   +12 more
core  

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

PD-L1 Expression in Muscle-Invasive Urinary Bladder Urothelial Carcinoma According to Basal/Squamous-Like Phenotype [PDF]

, 2020
Bohyun Kim, Chul Lee, Young A Kim, Kyung Chul Moon   +3 more
openalex   +1 more source

TONSL Promotes Hepatocellular Carcinoma Progression by Inhibiting Apoptosis Through Homologous Recombination Repair

Cancer Science, EarlyView.
In hepatocellular carcinoma, the 8q24.3 locus is frequently amplified and is associated with tumor‐specific overexpression of TONSL. TONSL promotes homologous recombination repair through RAD51, limits γH2AX accumulation and apoptosis, supports tumor growth, and its loss increases sensitivity to poly (ADP‐ribose) polymerase (PARP) inhibition.
Akinori Tsujimoto, Hajime Otsu, Takashi Ofuchi, Tomohiko Ikehara, Kosuke Hirose, Shohei Shibuta, Kazuki Omachi, Yu Takahashi, Yuya Ono, Satoshi Higuchi, Takanari Tatsumi, Kiyotaka Hosoda, Qingjiang Hu, Yusuke Yonemura, Takaaki Masuda, Masayuki Sho, Koshi Mimori   +16 more
wiley   +1 more source

Case Report: A Rare Case with Cutaneous Metastasis of Bladder Urothelial Carcinoma

Journal of Medical Sciences
Bladder cancer is a common genitourinary malignancy with variable metastatic potential. Cutaneous metastasis is uncommon and often presents with a poor prognosis.
Min-Jui Wu, Hui-Kung Ting, Ting-Ying Lee, Yu-Cing Juho   +3 more
doaj   +1 more source

A Phase I Trial of Intravesical Cabazitaxel, Gemcitabine and Cisplatin for the Treatment of Nonmuscle Invasive bacillus Calmette-Guérin Unresponsive or Recurrent/Relapsing Urothelial Carcinoma of the Bladder

, 2020
G. Joel DeCastro, Wilson Sui, Jamie S. Pak, Shing M. Lee, Dara Holder, Max M. Kates, Renu K. Virk, Charles G. Drake, Christopher B. Anderson, Bridget James, Cory Abate‐Shen, James M. McKiernan   +11 more
openalex   +2 more sources

Higher risk of urothelial carcinoma in the upper urinary tract than in the urinary bladder in hemodialysis patients [PDF]

, 2016
Po‐Jen Hsiao, Po‐Fan Hsieh, Chao-Hsiang Chang, Hsi‐Chin Wu, Chi‐Rei Yang, Chi‐Ping Huang   +5 more
openalex   +1 more source