Results 91 to 100 of about 864,284 (298)

The Effects of Air and Underwater Blast on Composite Sandwich Panels and Tubular Laminate Structures

, 2012
The resistance of glass-fibre reinforced polymer (GFRP) sandwich panels and laminate tubes to blast in air and underwater environments has been studied.
A Neuberger, A Neuberger, EH Wang, H. Arora, J LeBlanc, J. P. Dear, MS Hoo Fatt, P. A. Hooper, R Rajendran, SA Tekalur, SA Tekalur, SA Tekalur, VS Deshpande, YW Kwon   +13 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Application of CRISPR/Cas9 Genome Editing Technology for the Improvement of Crops Cultivated in Tropical Climates: Recent Progress, Prospects, and Challenges

Frontiers in Plant Science, 2018
The world population is expected to increase from 7.3 to 9.7 billion by 2050. Pest outbreak and increased abiotic stresses due to climate change pose a high risk to tropical crop production.
Effi Haque, Hiroaki Taniguchi, Md. Mahmudul Hassan, Md. Mahmudul Hassan, Pankaj Bhowmik, M. Rezaul Karim, Magdalena Śmiech, Kaijun Zhao, Mahfuzur Rahman, Tofazzal Islam, Tofazzal Islam   +10 more
doaj   +1 more source

Association between 5-Year clinical outcome in patients with nonmedically evacuated mild blast traumatic brain injury and clinical measures collected within 7 days postinjury in combat [PDF]

, 2019
Importance: Although previous work has examined clinical outcomes in combat-deployed veterans, questions remain regarding how symptoms evolve or resolve following mild blast traumatic brain injury (TBI) treated in theater and their association with long ...
Barber, Jason, Dikmen, Sureyya, Fann, Jesse R, Johnson, Ann M, Mac Donald, Christine L, Patterson, Jana, Temkin, Nancy   +6 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Neutrinos and Gamma Rays from Photomeson Processes in Gamma Ray Bursts

, 2003
Acceleration of high-energy hadrons in GRB blast waves will be established if high-energy neutrinos are detected from GRBs. Recent calculations of photomeson neutrino production are reviewed, and new calculations of high-energy neutrinos and the ...
Atoyan, A., Dermer, C. D.
core   +2 more sources

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

A synoptic literature review of animal models for investigating the biomechanics of knee osteoarthritis

Frontiers in Bioengineering and Biotechnology
Osteoarthritis (OA) is a common chronic disease largely driven by mechanical factors, causing significant health and economic burdens worldwide. Early detection is challenging, making animal models a key tool for studying its onset and mechanically ...
Luyang Xu, Luyang Xu, Zepur Kazezian, Zepur Kazezian, Andrew A. Pitsillides, Anthony M. J. Bull, Anthony M. J. Bull   +6 more
doaj   +1 more source

Environmental Impact on the Southeast Limb of the Cygnus Loop

, 2004
We analyze observations from the Chandra X-ray Observatory of the southeast knot of the Cygnus Loop supernova remnant. In this region, the blast wave propagates through an inhomogeneous environment.
James R. Graham, N. A. Levenson, Spitzer L., Jr.   +2 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source