Results 171 to 180 of about 1,862,609 (237)

The MoSR‐MoDde1 Regulatory Axis: A Novel Determinant of DMI Sensitivity and a Target for Sustainable Rice Blast Control

Advanced Science, EarlyView.
The transcription factor MoSR governs DMI fungicide sensitivity in Magnaporthe oryzae through dual regulation of ergosterol biosynthesis and the detoxification enzyme MoDde1. Targeting MoDde1 via a small‐molecule inhibitor or host‐induced gene silencing enhances DMI efficacy against rice blast, offering a sustainable disease management strategy ...
Fan‐Zhu Meng, Wen‐Kai Wei, Meng‐Yao Wu, Min‐Zheng Cai, Yu‐Fu Wang, Li Zhao, Shuai Meng, Liang‐Fen Yin, Guido Schnabel, Wei‐Xiao Yin, Chao‐Xi Luo   +10 more
wiley   +1 more source

Serotonin 5-HT2A receptor expression is chronically decreased in the anterior cerebral cortex of male rats following repetitive low-level blast exposure. [PDF]

Front Neurol
De Gasperi R, Perez Garcia G, Gama Sosa MA, Perez GM, Abutarboush R, Kawoos U, Hof PR, Zhu CW, Ahlers ST, Elder GA.   +9 more
europepmc   +1 more source

Blast Exposure Dysregulates Nighttime Melatonin Synthesis and Signaling in the Pineal Gland: A Potential Mechanism of Blast-Induced Sleep Disruptions. [PDF]

Brain Sci, 2022
Govindarajulu M, Patel MY, Wilder DM, Long JB, Arun P.   +4 more
europepmc   +1 more source

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

Advanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang, Zhenhua Hu, Jiali Liao, Lijun Huang, Jinyu Liu, Chen Tu, Yuchen Li, Lulu Xie, Shilei Bi, Xiaobo Fang, Jingsi Chen, Lili Du, Wei Sun, Haibin Wang, Shuang Zhang, Dunjin Chen, Zhaowei Tu   +16 more
wiley   +1 more source

The association between blast exposure and transdiagnostic health symptoms on systemic inflammation. [PDF]

Neuropsychopharmacology, 2022
Hayes JP, Pierce ME, Valerio KE, Miller MW, Huber BR, Fortier CB, Fonda JR, Milberg W, McGlinchey R.   +8 more
europepmc   +1 more source

Strengthening Constitutive Motifs in Isotropic Fibrous Hydrogel for Exceptional Damage Resistance

Advanced Science, EarlyView.
An orientation‐free strategy is reported for fabricating damage‐resistant hydrogels by strengthening constitutive motifs in isotropic fibrous (IF) networks. Through nonsolvent quenching followed by salting‐out, IF networks are generated and their multiscale constituents are subsequently reinforced, yielding dense and crystalline isotropic nanofiber ...
Bolin Wan, Xule Yang, Liju Xu, Dong Qiu
wiley   +1 more source

Low-Intensity Blast Exposure Induces Multifaceted Long-Lasting Anxiety-Related Behaviors in Mice. [PDF]

Neurotrauma Rep
Siedhoff HR, Chen S, Balderrama A, Jackson D, Li R, Sun GY, DePalma RG, Cui J, Gu Z.   +8 more
europepmc   +1 more source

Zinc Fingers as Programmable Metalloprotein Scaffolds for Altering Pathogenic Biomolecular Phase Transitions

Advanced Science, EarlyView.
Modular zinc finger (ZF) metalloproteins function as programmable biomolecular scaffolds that modulate pathogenic amyloid assembly. Through direct protein–protein interactions, ZF arrays alter amyloid phase behavior and redirect β‐sheet fibrillization toward nontoxic aggregates.
Seongmin Park, Yunha Hwang, Jimin Kwak, Yuxi Lin, Hye‐Yeon Park, Eunju Nam, Jiyeon Han, Soyeon Park, Hyunyong Kim, Ju‐Eun Kim, Hyun Goo Kang, Jiyong Park, Young‐Ho Lee, Kyoung‐Shim Kim, Chul‐Ho Lee, Seung Jae Lee, Mi Hee Lim   +16 more
wiley   +1 more source

Modeling Highly Repetitive Low-level Blast Exposure in Mice. [PDF]

J Vis Exp
Crabtree A, McEvoy C, Muench P, Ivory RA, Rodriguez J, Omer M, Charles T, Meabon JS.   +7 more
europepmc   +1 more source

Editorial: Neurosensory Alterations From Blast Exposure and Blunt Impact. [PDF]

Front Neurol, 2021
Sajja V, Long JB, Tenn CC.
europepmc   +1 more source