Results 191 to 200 of about 222,866 (288)

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source

Temporal Dynamics of Retinal Inflammation Following Blast Exposure in a Ferret Model. [PDF]

Neurotrauma Rep
Samdavid Thanapaul RJR, Pundkar C, Phuyal G, Govindarajulu MY, Menon A, Long JB, Arun P.   +6 more
europepmc   +1 more source

Repetitive Low-Level Blast Exposure via Akt/NF-κB Signaling Pathway Mediates the M1 Polarization of Mouse Alveolar Macrophage MH-S Cells. [PDF]

Int J Mol Sci, 2023
Geng C, Wang X, Chen J, Sun N, Wang Y, Li Z, Han L, Hou S, Fan H, Li N, Gong Y.   +10 more
europepmc   +1 more source

DUST MONITORING EXPOSURE: ABRASIVE BLASTING PROCESS [PDF]

International Journal of Engineering and Technology, 2016
Hanis Zakaria, Norzelawati Asmuin, Muhamad Nurmizan Ahmad, Norhalim Hassan, Mohamad Farid Sies   +4 more
openaire   +1 more source

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

Chronic Neurobehavioral and Neuropathological Consequences of Repeated Blast Exposure in P301S Transgenic Tau Rats. [PDF]

Neurotrauma Rep
Robey C, Grillakis A, Fan A, Liu J, Tucker LB, Fu AH, Kim Y, McCabe JT.   +7 more
europepmc   +1 more source

Protective Performance of Helmets and Goggles in Mitigating Brain Biomechanical Response to Primary Blast Exposure. [PDF]

Ann Biomed Eng, 2022
Yu X, Ghajari M.
europepmc   +1 more source

Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer

Advanced Science, EarlyView.
Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen, Dingru Li, Yingna Liao, Zehua Wang, Chunbin Zhu, Zifeng Zhang, Liquan Jin, Yueyue Chen, Jiaoshun Chen, Junyi Xu, Miaoyan Wei, Rong Tang, Xianjun Yu, Si Shi   +13 more
wiley   +1 more source

Blast-Related Mild Traumatic Brain Injury: Case Report Highlighting the Long-Term Neurocognitive Sequelae Following Blast Exposure in Veterans. [PDF]

Cureus
Holm D, Tasarz J, Ponamala M, Chung D.
europepmc   +1 more source

Repetitive Blast Exposure Increases Appetitive Motivation and Behavioral Inflexibility in Male Mice. [PDF]

Front Behav Neurosci, 2021
Baskin B, Lee SJ, Skillen E, Wong K, Rau H, Hendrickson RC, Pagulayan K, Raskind MA, Peskind ER, Phillips PEM, Cook DG, Schindler AG.   +11 more
europepmc   +1 more source