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Stability of African swine fever virus genome under different environmental conditions [PDF]
Veterinary World, 2023 Background and Aim: African swine fever (ASF), a globally transmitted viral disease caused by ASF virus (ASFV), can severely damage the global trade economy.
Wei Zheng +8 more
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Bcl-xL Promotes the Survival of Motor Neurons Derived from Neural Stem Cells
Biology, 2023 Neural stem cell (NSC) transplantation creates new hope for the treatment of neurodegenerative disorders by direct differentiation into neurons. However, this technique is limited by poor survival and functional neuron deficiency. In this research study,
Yunqin Wu +11 more
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Generation of hiPSCs with ABO c.767T>C substitution: resulting in splicing variants
Frontiers in Genetics, 2023 Introduction: The ABO blood group system has important clinical significance in the safety of blood transfusion and organ transplantation. Numerous ABO variations, especially variations in the splice sites, have been identified to be associated with some
Yinge Jin +12 more
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Scientific Reports, 2022 Group sizes in an animal study are calculated from estimates on variation, effect, power and significance level. Much of the variation in glucose related parameters of the diet-induced obese (DIO) mouse model is due to inter-individual variation in gut ...
Valeriia Bondarenko +9 more
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Animals, 2023 Widely used as a flame retardant, 2,2′4,4′-tetrabromodiphenyl ether (BDE-47) is a persistent environmental pollutant with toxicological effects, including hepatotoxicity, neurotoxicity, reproductive toxicity, and endocrine disruption.
Rong-Ping Liu +8 more
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British Medical Bulletin, 2000 Animal models of cerebral ischaemia mimic at best less than 25% of all strokes. Compounds which prove efficacious in animal models should, therefore, only be expected to improve outcome in a quarter of all strokes. If trials for acute stroke are to succeed, stroke subgroups represented by the animal models should be targeted. For the other subgroups, e.
Small, D, Buchan, A
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Advantages and Progress of Using Chinese Hamsters to Construct Disease Models
Shiyan dongwu yu bijiao yixue, 2021 Chinese hamsters are experimental animals originally from China. They play an important role in experimental research on medicine and biology. They are widely used in life science research, such as genetics, infectious diseases, tissue culture ...
GAO Jiping +4 more
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Animal Models in Osteosarcoma [PDF]
Frontiers in Oncology, 2014 Osteosarcoma (OS) is the most common non-hematologic primary tumor of bone in children and adults. High-dose cytotoxic chemotherapy and surgical resection have improved prognosis, with long-term survival for non-metastatic disease approaching 70%. However, most OS tumors are high grade and tend to rapidly develop pulmonary metastases.
Guijarro, Maria V. +2 more
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Generation of a homozygous RANGRF knockout hiPSC line by CRISPR/Cas9 system
Stem Cell Research, 2023 The RAN Guanine Nucleotide Release Factor (RANGRF) gene encodes the protein MOG1, which binds to Nav1.5 and facilitates its transport to the cell membrane. Nav1.5 mutations have been linked to various cardiac arrhythmias and cardiomyopathy.
Meiling Jiang +7 more
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Nature Communications, 2021 TARM1 is a LILR family member that drives cell signalling via interactions with FcRγ. Here the authors show that TARM1 binds collagens to activate dendritic cells and thereby is an effector of inflammatory arthritis, plus provide a soluble TARM-Fc fusion
Rikio Yabe +10 more
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