Results 11 to 20 of about 1,661,237 (266)

Animal Models in Osteosarcoma [PDF]

open access: yesFrontiers in Oncology, 2014
Osteosarcoma (OS) is the most common non-hematologic primary tumor of bone in children and adults. High-dose cytotoxic chemotherapy and surgical resection have improved prognosis, with long-term survival for non-metastatic disease approaching 70%. However, most OS tumors are high grade and tend to rapidly develop pulmonary metastases.
Guijarro, Maria V.   +2 more
openaire   +3 more sources

Fisetin may protect early porcine embryos from oxidative stress by down-regulating GRP78 levels [PDF]

open access: yesPeerJ
Fisetin is a natural flavonol with a variety of biological activities, including anti-inflammatory and antitumor activities. However, the effect of fisetin on mammalian oocyte and embryo development is unknown, so in this study, we used porcine oocytes ...
Xiu-Wen Yuan   +9 more
doaj   +2 more sources

Animating Volumetric Models

open access: yesGraphical Models, 2001
Summary: This paper describes a technique to animate three-dimensional sampled volumes. The technique gives the animator the ability to treat volumes as if they were standard polygonal models and to use all of the standard animation/motion capture tools on volumetric data.
Nikhil Gagvani, Deborah Silver
openaire   +1 more source

Generation of human induced pluripotent stem cells carrying albumin-sfGFP reporter

open access: yesStem Cell Research
Current methodologies for hepatocyte induction from human induced pluripotent stem cells (hiPSCs) have limited efficacy due to lack of a functional hepatocyte reporter.
Jinling Wang   +10 more
doaj   +1 more source

Therapeutic potential of human umbilical cord mesenchymal stem cells on aortic atherosclerotic plaque in a high-fat diet rabbit model

open access: yesStem Cell Research & Therapy, 2021
Background Atherosclerosis (AS) is a complex disease caused in part by dyslipidemia and chronic inflammation. AS is associated with serious cardiovascular disease and remains the leading cause of mortality worldwide.
Yanhong Li   +8 more
doaj   +1 more source

Animal Models of Atherosclerosis [PDF]

open access: yes, 2012
Cardiovascular disease is currently the predominant cause of mortality worldwide and its incidence is expected to increase significantly during the next decades owing to the unhealthy effects of modern lifestyle habits (e.g., obesity and lack of physical exercise). Cardiovascular death is frequently associated with acute myocardial infarction or stroke,
Fuster, Jose J.   +4 more
openaire   +3 more sources

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian   +13 more
wiley   +1 more source

Animal Model of Dermatophytosis [PDF]

open access: yesJournal of Biomedicine and Biotechnology, 2012
Dermatophytosis is superficial fungal infection caused by dermatophytes that invade the keratinized tissue of humans and animals. Lesions from dermatophytosis exhibit an inflammatory reaction induced to eliminate the invading fungi by using the host’s normal immune function.
Shimamura, Tsuyoshi   +2 more
openaire   +2 more sources

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan   +1 more
wiley   +1 more source

A novel efficient strategy to generate liver sinusoidal endothelial cells from human pluripotent stem cells

open access: yesScientific Reports
Liver sinusoidal endothelial cells (LSECs) are highly specialized endothelial cells (ECs) that play an important role in liver development and regeneration. Additionally, it is involved in various pathological processes, including steatosis, inflammation,
Shang-Ping Tian   +7 more
doaj   +1 more source

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