Results 71 to 80 of about 143,268 (301)

Exposure to mild blast forces induces neuropathological effects, neurophysiological deficits and biochemical changes

Molecular Brain, 2018
Direct or indirect exposure to an explosion can induce traumatic brain injury (TBI) of various severity levels. Primary TBI from blast exposure is commonly characterized by internal injuries, such as vascular damage, neuronal injury, and contusion ...
Adan Hernandez, Chunfeng Tan, Florian Plattner, Aric F. Logsdon, Karine Pozo, Mohammad A. Yousuf, Tanvir Singh, Ryan C. Turner, Brandon P. Luke-Wold, Jason D. Huber, Charles L. Rosen, James A. Bibb   +11 more
doaj   +1 more source

Neuronal Injury and Glial Changes Are Hallmarks of Open Field Blast Exposure in Swine Frontal Lobe. [PDF]

PLoS ONE, 2017
With the rapid increase in the number of blast induced traumatic brain injuries and associated neuropsychological consequences in veterans returning from the operations in Iraq and Afghanistan, the need to better understand the neuropathological sequelae
Srinivasu Kallakuri, Alok Desai, Ke Feng, Sharvani Tummala, Tal Saif, Chaoyang Chen, Liying Zhang, John M Cavanaugh, Albert I King   +8 more
doaj   +1 more source

Links between traumatic brain injury and ballistic pressure waves originating in the thoracic cavity and extremities

, 2008
Identifying patients at risk of traumatic brain injury (TBI) is important because research suggests prophylactic treatments to reduce risk of long-term sequelae.
Alexander MP, Amy Courtney, Bruton C, Center for Disease Control and Prevention (CDC), Cernak I, Cernak I, Courtney M, Courtney M, Herrmann M, Krave U, Kushner DS, Kushner DS, Lowenstein DH, Margerison JH, Mayorga MA, Michael Courtney, Newgard K, Scott SG, Shaw NA, Stalnacke BM, Suneson A, Suneson A, Suneson A, Thompson HJ, Toth Z, Treib J, Trudeau DL, Vanderploeg RD, Vink R, Wang Q   +29 more
core   +1 more source

Enhanced Endoscopic Internal Drainage of Gastric Abscess Through Additively Manufactured Stents

Advanced Healthcare Materials, EarlyView.
Postoperative gastric leaks are often treated with off‐label biliary double‐pigtail stents, yet conventional extruded designs are not optimized for leak anatomy, can migrate, and may limit abscess evacuation. PETALS is introduced to optimize transmural drainage geometry and enable patient‐specific 3D‐printable stents.
Parima Phowarasoontorn, Yongbin Ko, Juan S. Barajas‐Gamboa, Juan P. Pantoja, Oraib Al‐Ketan, Mohamed Ali, Sungyun Sohn, Heba Tageldeen Naser, Abdel‐Hameed Dabbour, Batoul Khlaifat, Ahmed AlZubaidi, Carlos Abril Vega, John Rodriguez, Matthew Kroh, Khalil B. Ramadi   +14 more
wiley   +1 more source

Mathematical models of blast induced TBI: current status, challenges and prospects

Frontiers in Neurology, 2013
Blast induced traumatic brain injury (TBI) has become a signature wound of recent military activities and is the leading cause of death and long-term disability among U.S. soldiers. The current limited understanding of brain injury mechanisms impedes the
Raj K Gupta, Andrzej ePrzekwas
doaj   +1 more source

Research Advances: January 2014 [PDF]

, 2014
The VA has a comprehensive research agenda to help the newest generation of Veterans -- those returning from operations Enduring Freedom, Iraqi Freedom, and New Dawn.

core  

Computational and in vitro studies of blast-induced blood-brain barrier disruption

, 2015
There is growing concern that blast-exposed individuals are at risk of developing neurological disorders later in life. Therefore, it is important to understand the dynamic properties of blast forces on brain cells, including the endothelial cells that ...
Banks, William A., Cook, David G., Del Razo, Mauricio J., Huber, B. Russell, Leveque, Randall J., Meabon, James S., Morofuji, Yoichi, Mourad, Pierre D., Peskind, Elaine R.   +8 more
core   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Biomechanical Tolerance of Whole Lumbar Spines in Straightened Posture Subjected to Axial Acceleration [PDF]

, 2017
Quantification of biomechanical tolerance is necessary for injury prediction and protection of vehicular occupants. This study experimentally quantified lumbar spine axial tolerance during accelerative environments simulating a variety of military and ...
Baisden, Jamie L., Chirvi, Sajal, Curry, William H., Doan, Ninh, Maiman, Dennis J., Paskoff, Glenn, Pintar, Frank A., Shender, Barry S., Stemper, Brian D., Yoganandan, Narayan   +9 more
core   +2 more sources

Anti‐Slip Material‐Based Strategies and Approaches

Advanced Materials Technologies, EarlyView.
This review highlights the principle mechanisms of slipping at the microscale, linking contact mechanics with a friction behavior model for surface interfaces. Main strategies to develop anti‐slip properties to the surfaces are discussed alongside standardized testing approaches.
Sogand Abbaspoor‐Zanjani, Carlo Antonini, Teresa Gatti, Mengjiao Wang   +3 more
wiley   +1 more source