Results 41 to 50 of about 4,992,809 (126)

Blastic plasmacytoid dendritic cell neoplasm presenting as violaceous forehead plaque [PDF]

, 2022
A 72-year-old man with a history of squamous cell carcinoma presented to the Portland VA with forehead discoloration. He was initially diagnosed with actinic damage and prescribed topical treatment.
Hopkins, Amy, Scopetta, John P, Knapp, Calvin, Kulkarni, Raj, Morrison, Georgia Mae   +4 more
core   +1 more source

Blastic plasmacytoid dendritic cell neoplasm in children: diagnostic features and clinical implications

Haematologica, 2010
Background Blastic plasmacytoid dendritic cell neoplasm is a rare malignancy that typically follows a highly aggressive clinical course in adults, whereas experience in children with this disease is very limited.Design and Methods This retrospective ...
Armin G. Jegalian, Nataliya P. Buxbaum, Fabio Facchetti, Mark Raffeld, Stefania Pittaluga, Alan S. Wayne, Elaine S. Jaffe   +6 more
doaj   +1 more source

Blastic Plasmacytoid Dendritic Cell Neoplasm Mimicking Erythema Nodosum: A Case Report

Annals of Internal Medicine: Clinical Cases, 2023
Blastic plasmacytoid dendritic cell neoplasm (BPDCN), previously known as blastic natural killer cell lymphoma, is a rare, difficult-to-diagnose, and aggressive hematologic malignancy.
Marino Hirata, Nozomu Yoshino, Maya Takazawa, Hisashi Oshiro, Shinichi Kako, Hitoshi Sugawara   +5 more
doaj   +1 more source

Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm

New England Journal of Medicine, 2019
Blastic plasmacytoid dendritic-cell neoplasm (BPDCN) is an aggressive hematologic cancer that is caused by transformed plasmacytoid dendritic cells that overexpress interleukin-3 receptor subunit alpha (IL3RA or CD123). Tagraxofusp (SL-401) is a CD123-directed cytotoxin consisting of human interleukin-3 fused to truncated diphtheria toxin.In this open ...
Naveen, Pemmaraju, Andrew A, Lane, Kendra L, Sweet, Anthony S, Stein, Sumithira, Vasu, William, Blum, David A, Rizzieri, Eunice S, Wang, Madeleine, Duvic, J Mark, Sloan, Sharon, Spence, Shay, Shemesh, Christopher L, Brooks, John, Balser, Ivan, Bergstein, Jeffrey E, Lancet, Hagop M, Kantarjian, Marina, Konopleva   +17 more
openaire   +2 more sources

Regimen of Azacitidine Combined with GemOx in the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm: A Case Report

Xiehe Yixue Zazhi, 2022
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a highly malignant hematological tumor derived from the precursor cells of plasmacytoid dendritic cells.
CHEN Xiaojun, LIU Yanquan, HU Xiaomei, HUANG Surong, SHEN Jianzhen   +4 more
doaj   +1 more source

Blastic Plasmacytoid Dendritic Cell Neoplasm; A Report of Three Cases [PDF]

Iranian Journal of Medical Sciences, 2019
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematodermic myeloid malignancy that is known to be derived from plasmacytoid dendritic cells which are characterized by expression of CD4, CD56, and more specific markers such as CD123. Here,
Akbar Safaei, Ahmad Monabati, Maral Mokhtari, Freidoon Solhjoo, Mehdi Montazer   +4 more
doaj   +1 more source

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

British Journal of Pharmacology, EarlyView.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source

Blastic Plasmacytoid Dendritic cell neoplasm: Case report / Neoplasia de células Dendríticas Plasmocitóides Blásticas: Relato de caso [PDF]

, 2021
Blastic plasmacytoid dendritic cell neoplasm is a rare neoplasm of hematopoietic origin with poor clinical evolution. Here we report a case of a patient who presented with blastic plamacytoid dendritic cell neoplasm with cutaneous and nodal involvement ...
Sallum, Michel Hamui, de Souza, Helio Moraes, da Silva, Vanessa Afonso, de Vito, Fernanda Bernadelli   +3 more
core   +1 more source

Indispensable role of immunophenotyping in diagnosing leukemic phase of blastic plasmacytoid dendritic cell neoplasm without cutaneous manifestation

Leukemia Research Reports, 2022
Blastic plasmacytoid dendritic cell neoplasm usually presents as skin lesions. Diagnostic error occurs when it primarily presents in leukemic phase without skin involvement.
Hareem Alam, Nabiha Saeed, Anila Rashid
doaj   +1 more source

Cutaneous involvement by myeloid leukaemias: challenging cases with important implications

Histopathology, EarlyView.
Myeloid leukaemias and precursors involving the skin are often challenging to diagnose with varied and overlapping clinical and histopathologic features. Nonetheless, they are critical for pathologists to recognize and accurately classify. This review discusses the clinical, histopathological and genetic features of myelodysplasia cutis (A) and ...
Alexandra C. Hristov
wiley   +1 more source