Results 41 to 50 of about 3,241 (183)

Successful outcome of second allogeneic bone marrow transplantation for blastic plasmacytoid dendritic cell neoplasm with MYC locus rearrangement

Leukemia Research Reports, 2019
A 62-year-old male was diagnosed with blastic plasmacytoid dendritic cell neoplasm (BPDCN) with a MYC rearrangement. Four months after the first unrelated bone marrow transplantation (BMT), he developed the relapsed BPDCN.
Takeharu Kato, Hidehiro Itonaga, Jun Taguchi, Junya Makiyama, Machiko Fujioka, Masataka Taguchi, Makiko Horai, Yasushi Sawayama, Daisuke Niino, Yoshitaka Imaizumi, Tomoko Hata, Shinichiro Yoshida, Kana Sakamoto, Kengo Takeuchi, Koichi Ohshima, Yasushi Miyazaki   +15 more
doaj   +1 more source

ZEB proteins in leukemia : friends, foes, or friendly foes? [PDF]

, 2018
. ZEB1 and ZEB2 play pivotal roles in solid cancer metastasis by allowing cancer cells to invade and disseminate through the transcriptional regulation of epithelial-to-mesenchymal transition.
Berx, Geert, Goossens, Steven, Schwaller, Jürg, Soen, Bieke, Van Vlierberghe, Pieter, Vandamme, Niels   +5 more
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Enhancement of the antigen-specific cytotoxic T lymphocyte-inducing ability in the PMDC11 leukemic plasmacytoid dendritic cell line via lentiviral vector-mediated transduction of the caTLR4 gene. [PDF]

, 2015
The aim of the present study was to enhance the efficiency of leukemia immunotherapy by increasing the antigen-specific cytotoxic T lymphocyte-inducing ability of leukemia cells. The leukemic plasmacytoid dendritic cell line PMDC05 containing the HLA-A02/
Bonehill, Aude, Hashimoto, Shigeo, Iwabuchi, Minami, Iwaya, Shunpei, Kasahara, Noriyuki, Narita, Miwako, Nishizawa, Yoshinori, Oiwa, Eri, Takahashi, Masuhiro, Takizawa, Jun, Uchiyama, Takayoshi   +10 more
core   +1 more source

Allogeneic Hematopoietic Cell Transplantation for Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) [PDF]

, 2021
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is an aggressive hematological malignancy; however, some patients achieve durable remission with allogeneic hematopoietic cell transplantation (allo-HCT).
Ahmed, Sairah, Al-Atrash, Gheath, Bashir, Qaiser, Champlin, Richard E, Hosing, Chitra, Kebriaei, Partow, Khouri, Issa F, Konopleva, Marina Y, Milton, Denái R, Nieto, Yago, Olson, Amanda L, Oran, Betul, Pemmaraju, Naveen, Popat, Uday R, Qazilbash, Muzaffar H, Rezvani, Katayoun, Rondon, Gabriela, Saini, Neeraj Y, Shpall, Elizabeth J, Srour, Samer A   +19 more
core   +2 more sources

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors [PDF]

, 2017
Dendritic cells (DCs) and monocytes play a central role in pathogen sensing, phagocytosis, and antigen presentation and consist of multiple specialized subtypes. However, their identities and interrelationships are not fully understood.
Butler, Andrew, De Jager, Philip L., Dixon, David, Filby, Andrew, Fletcher, James, Griesbeck, Morgane, Grundberg, Ida, Hacohen, Nir, Haniffa, Muzlifah, Jardine, Laura, Lane, Andrew A., Lazo, Suzan, Li, Weibo, McDonald, David, Nilsson, Emil, Regev, Aviv, Reynolds, Gary, Rozenblatt-Rosen, Orit, Sarkizova, Siranush, Satija, Rahul, Shekhar, Karthik, Stephenson, Emily, Villani, Alexandra-Chloé, Zheng, Shiwei   +23 more
core   +1 more source

Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis [PDF]

, 2022
open30siBlastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive leukemia of plasmacytoid dendritic cells (pDC). BPDCN occurs at least three times more frequently in men than in women, but the reasons for this sex bias are unknown.

core   +1 more source

Blastic plasmacytoid dendritic cell neoplasm

, 2017
Blastic plasmacytoid dendritic cell neoplasm is an aggressive malignant neoplasm originating from precursor plasmacytoid dendritic cells. Blastic plasmacytoid dendritic cell neoplasm shows a characteristic immunophenotype in which the tumor cells express CD4, CD56, TCL1, and bright CD123, and lack expression of lineage-specific myeloid and lymphoid ...
Yuranga Weerakkody, Tom Foster, Daniel Bell   +2 more
  +6 more sources

Blastic plasmacytoid dendritic cell neoplasm in children: diagnostic features and clinical implications

Haematologica, 2010
Background Blastic plasmacytoid dendritic cell neoplasm is a rare malignancy that typically follows a highly aggressive clinical course in adults, whereas experience in children with this disease is very limited.Design and Methods This retrospective ...
Armin G. Jegalian, Nataliya P. Buxbaum, Fabio Facchetti, Mark Raffeld, Stefania Pittaluga, Alan S. Wayne, Elaine S. Jaffe   +6 more
doaj   +1 more source

Blastic Plasmacytoid Dendritic Cell Neoplasm Mimicking Erythema Nodosum: A Case Report

Annals of Internal Medicine: Clinical Cases, 2023
Blastic plasmacytoid dendritic cell neoplasm (BPDCN), previously known as blastic natural killer cell lymphoma, is a rare, difficult-to-diagnose, and aggressive hematologic malignancy.
Marino Hirata, Nozomu Yoshino, Maya Takazawa, Hisashi Oshiro, Shinichi Kako, Hitoshi Sugawara   +5 more
doaj   +1 more source

Blastic Plasmacytoid Dendritic Cell Neoplasm; A Report of Three Cases [PDF]

Iranian Journal of Medical Sciences, 2019
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematodermic myeloid malignancy that is known to be derived from plasmacytoid dendritic cells which are characterized by expression of CD4, CD56, and more specific markers such as CD123. Here,
Akbar Safaei, Ahmad Monabati, Maral Mokhtari, Freidoon Solhjoo, Mehdi Montazer   +4 more
doaj   +1 more source