Results 21 to 30 of about 2,136 (172)

A Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Extensively Studied by Flow Cytometry and Immunohistochemistry

Case Reports in Hematology, 2017
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with aggressive clinical course and poor prognosis. Diagnosis is based on detection of CD4+ CD56+, CD123high, TCL-1+, and blood dendritic cell antigen-2/CD303+ blasts ...
Martina Pennisi, Clara Cesana, Micol Giulia Cittone, Laura Bandiera, Barbara Scarpati, Valentina Mancini, Silvia Soriani, Silvio Veronese, Mauro Truini, Silvano Rossini, Roberto Cairoli   +10 more
doaj   +2 more sources

Reduced intensity allogeneic stem cell transplant for treatment of blastic plasmacytoid dendritic cell neoplasm [PDF]

Hematology Reports, 2014
Blastic plasmacytoid dendritic cell neoplasm is a rare, aggressive tumor characterized by skin and/or marrow infiltration by CD4+ CD56+ cells. Historically, the tumor was variably thought to arise from either monocytes, T cells or NK cells giving rise to
Anand Lokare, Emmanouil Nikolousis, Neil Phillips, Zbignieuw Rudzki, Richard Lovell, Bhuvan Kishore, Don Milligan, Shankara Paneesha   +7 more
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Blastic plasmacytoid dendritic cell neoplasm: challenges and future prospects

Blood and Lymphatic Cancer: Targets and Therapy, 2017
Amy M Trottier, Sonia Cerquozzi, Carolyn J Owen Division of Hematology and Hematological Malignancies, University of Calgary, Foothills Medical Centre, Calgary, AB, Canada Abstract: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare CD4+ CD56+
Trottier AM, Cerquozzi S, Owen CJ
doaj   +1 more source

Blastic Plasmacytoid Dendritic Cell Neoplasm

Current Hematologic Malignancy Reports, 2018
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare malignancy derived from plasmacyoid dendritic cells whose biology, clinical features, and treatment options are increasingly better understood.TCF4 is a master regulator that drives donwstream transcriptional programs in BPDCN.
Manoj Ponadka Rai, Prabhjot Singh Bedi, Samanjit Kaur Kandola, Shilpa Kavuturu, Rashi Singhal   +4 more
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Rapidly progressing blastic plasmacytoid dendritic cell neoplasm causing diffuse skin thickening: A case report with sequential computed tomography examinations

Radiology Case Reports, 2021
Blastic plasmacytoid dendritic cell neoplasm is a rare aggressive myeloid malignancy thought to be derived from precursor plasmacytoid dendritic cells. Rapid progression and poor prognosis have been known.
Kyohei Yoshioka, Ryo Kurokawa, Shiori Amemiya, Hiroaki Koyamaa, Kensuke Matsuda, Akira Honda, Mineo Kurokawa, Aya Shinozaki-Ushiku, Osamu Abe   +8 more
doaj   +1 more source

A misdiagnosed case of blastic plasmacytoid dendritic cell neoplasm experiencing multiple recurrences who underwent allogeneic stem cell transplantation: a case report

Journal of Medical Case Reports, 2021
Background Blastic plasmacytoid dendritic cell neoplasm represents a rare type of hematologic malignancy that often manifests itself through various skin lesions. It commonly affects the elderly male population.
Fateme Salemi, Seyed Mohammad Reza Mortazavizadeh, Seyyedmohammadsadeq Mirmoeeni, Amirhossein Azari Jafari, Farid Kosari, Seyed Sina Naghibi Irvani   +5 more
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Pathomorphological and clinical characteristics of blastic plasmocytoid dendritic cell neoplasm. Case report

Терапевтический архив, 2022
The paper reveals the 5 cases date about blastic plasmacytoid dendritic cell neoplasm. The presented information demonstrates morphological, immunohistochemical data and clinical manifestations.
Andrei A. Sherstnev, Alla M. Kovrigina, Tatiana I. Solovyova, Tatiana N. Moiseeva   +3 more
doaj   +1 more source

Blastic plasmacytoid dendritic cell neoplasm in a young patient [PDF]

, 2021
Blastic plasmacytoid dendritic cell neoplasm is a rare hematologic neoplasm originating from plasmacytoid dendritic cell precursors that has an aggressive disease course with typically poor prognosis.
Harker, David, Li, Jeffrey N, Dominguez, Arturo, Vandergriff, Travis   +3 more
core   +1 more source

Pediatric Blastic Plasmacytoid Dendritic Cell Neoplasm: A Case Report [PDF]

Clinical Pathology
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive neoplastic process of precursor plasmacytoid dendritic cells. The diagnostic evaluation of this heterogenous entity is challenging, requiring a comprehensive approach of ...
Jasper X Zheng, Elham Vali Betts, Denis M Dwyre, Jong H Chung, Ananya Datta Mitra   +4 more
doaj   +2 more sources

Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells

Nature Communications, 2022
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematologic malignancy derived from the precursors of plasmacytoid dendritic cells.
Tianyu Cai, Agnès Gouble, Kathryn L. Black, Anna Skwarska, Ammar S. Naqvi, Deanne Taylor, Ming Zhao, Qi Yuan, Mayumi Sugita, Qi Zhang, Roman Galetto, Stéphanie Filipe, Antonio Cavazos, Lina Han, Vinitha Kuruvilla, Helen Ma, Connie Weng, Chang-Gong Liu, Xiuping Liu, Sergej Konoplev, Jun Gu, Guilin Tang, Xiaoping Su, Gheath Al-Atrash, Stefan Ciurea, Sattva S. Neelapu, Andrew A. Lane, Hagop Kantarjian, Monica L. Guzman, Naveen Pemmaraju, Julianne Smith, Andrei Thomas-Tikhonenko, Marina Konopleva   +32 more
doaj   +1 more source