Clinical, Cosmetic and Investigational Dermatology, 2023 Fang Liu,1 Fei Qi,2 Jingya Zhang,1 Yaqi Tan,1 Xiuying Zhang1 1Department of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Dermatology, Peking Union Medical College Hospital ...
Liu F, Qi F, Zhang J, Tan Y, Zhang X
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A novel mutation of IFT140 in a preschool child with Mainzer-Saldino syndrome accompanied by rare tumor blastic plasmacytoid dendritic cell neoplasm: a case report [PDF]
BMC PediatricsBackground Mainzer-Saldino syndrome is a rare autosomal recessive ciliopathy characterized by cone-shaped epiphyses, chronic renal failure, and early-onset severe retinal dystrophy.
Ruolan Hu +3 more
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Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm
New England Journal of Medicine, 2019 Blastic plasmacytoid dendritic-cell neoplasm (BPDCN) is an aggressive hematologic cancer that is caused by transformed plasmacytoid dendritic cells that overexpress interleukin-3 receptor subunit alpha (IL3RA or CD123). Tagraxofusp (SL-401) is a CD123-directed cytotoxin consisting of human interleukin-3 fused to truncated diphtheria toxin.In this open ...
Andrew A Lane +2 more
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Successful outcome of second allogeneic bone marrow transplantation for blastic plasmacytoid dendritic cell neoplasm with MYC locus rearrangement [PDF]
Leukemia Research Reports, 2019 A 62-year-old male was diagnosed with blastic plasmacytoid dendritic cell neoplasm (BPDCN) with a MYC rearrangement. Four months after the first unrelated bone marrow transplantation (BMT), he developed the relapsed BPDCN.
Takeharu Kato +15 more
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Blastic plasmacytoid dendritic cell neoplasm: Report of two pediatric cases
Indian Journal of Pathology and Microbiology, 2015 Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare subtype of acute leukemia that typically follows a highly aggressive clinical course in adults, whereas experience in children with this disease is very limited.
Preeti Ashok Dharmani +6 more
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Blastic Plasmacytoid Dendritic-Cell Neoplasm [PDF]
New England Journal of Medicine, 2020 Blastic Plasmacytoid Dendritic-Cell Neoplasm A 29-year-old man presented with progressive skin lesions on the face, back, trunk, and limbs.
Yung Gonzaga, Mayne Fontes
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Indispensable role of immunophenotyping in diagnosing leukemic phase of blastic plasmacytoid dendritic cell neoplasm without cutaneous manifestation [PDF]
Leukemia Research Reports, 2022 Blastic plasmacytoid dendritic cell neoplasm usually presents as skin lesions. Diagnostic error occurs when it primarily presents in leukemic phase without skin involvement.
Hareem Alam, Nabiha Saeed, Anila Rashid
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Case Reports in Hematology, 2017 Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with aggressive clinical course and poor prognosis. Diagnosis is based on detection of CD4+ CD56+, CD123high, TCL-1+, and blood dendritic cell antigen-2/CD303+ blasts ...
Martina Pennisi +10 more
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Reduced intensity allogeneic stem cell transplant for treatment of blastic plasmacytoid dendritic cell neoplasm [PDF]
Hematology Reports, 2014 Blastic plasmacytoid dendritic cell neoplasm is a rare, aggressive tumor characterized by skin and/or marrow infiltration by CD4+ CD56+ cells. Historically, the tumor was variably thought to arise from either monocytes, T cells or NK cells giving rise to
Anand Lokare +7 more
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Blastic plasmacytoid dendritic cell neoplasm: genomics mark epigenetic dysregulation as a primary therapeutic target [PDF]
Haematologica, 2019 Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy for which there is still no effective therapy. In order to identify genetic alterations useful for a new treatment design, we used whole-exome sequencing
Maria Rosaria Sapienza +30 more
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