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Tagraxofusp for blastic plasmacytoid dendritic cell neoplasm [PDF]

open access: yesHaematologica, 2023
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy that presents with characteristic dark purple skin papules, plaques, and tumors, but may also involve the bone marrow, blood, lymph nodes, and central nervous system ...
Marlise R. Luskin, Andrew A. Lane
doaj   +4 more sources

Blastic plasmacytoid dendritic cell neoplasm [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2013
Blastic plasmacytoid dendritic cell neoplasm is a rare and aggressive hematodermic neoplasia with frequent cutaneous involvement and leukemic dissemination.
André Lencastre   +5 more
doaj   +15 more sources

Blastic Plasmacytoid Dendritic Cell Neoplasm [PDF]

open access: yesHematology/Oncology Clinics of North America, 2020
Blastic Plasmacytoid Dendritic-Cell Neoplasm A 29-year-old man presented with progressive skin lesions on the face, back, trunk, and limbs.
John T O'Malley
exaly   +11 more sources

Blastic plasmacytoid dendritic cell neoplasm [PDF]

open access: yesBlood, 2012
![Figure][1] An 81-year-old man had multiple skin lesions (brown-red plaques on the face, abdomen, and back) and asthenia. There was no hepatosplenomegaly or adenopathy. Despite normal blood count values, the peripheral smear contained blasts (7%).
Francine Garnache-Ottou   +1 more
exaly   +4 more sources

Blastic plasmacytoid dendritic cell neoplasm [PDF]

open access: yesMedicina Clínica (English Edition)
Blastic plasmacytoid dendritic cell neoplasm is an uncommon, aggressive hematologic neoplasm carrying a poor prognosis with a median survival of one year, making early detection vital. Patients present with a number of characteristic cutaneous manifestations and are treated with chemotherapy and hematopoietic stem cell transplantation, which may ...
Lasheras-Pérez MA   +2 more
europepmc   +9 more sources

A novel mutation of IFT140 in a preschool child with Mainzer-Saldino syndrome accompanied by rare tumor blastic plasmacytoid dendritic cell neoplasm: a case report [PDF]

open access: yesBMC Pediatrics
Background Mainzer-Saldino syndrome is a rare autosomal recessive ciliopathy characterized by cone-shaped epiphyses, chronic renal failure, and early-onset severe retinal dystrophy.
Ruolan Hu   +3 more
doaj   +2 more sources

Juvenile Blastic Plasmacytoid Dendritic Cell Neoplasm

open access: yesActa Dermato-Venereologica, 2020
is missing (Short communication)
Kinan M. Hayani   +4 more
doaj   +3 more sources

Blastic Plasmacytoid Dendritic Cell Neoplasm on the Scalp [PDF]

open access: yesCase Reports in Dermatology, 2011
We describe a 75-year-old Japanese woman with blastic plasmacytoid dendritic cell neoplasm. On her first visit, there were multiple areas of disseminated, elastic hard nodules with multicentric purpura on her scalp.
Sawako Fukushi   +2 more
doaj   +3 more sources

CT findings associated with blastic plasmacytoid dendritic cell neoplasm: a case report

open access: yesActa Radiologica Open, 2016
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy that is frequently misdiagnosed. We present a case of a 53-year-old man diagnosed with blastic plasmacytoid dendritic cell neoplasm with extensive computed tomography ...
Daniel Jeong   +3 more
doaj   +2 more sources

Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm

open access: yesNew England Journal of Medicine, 2019
Blastic plasmacytoid dendritic-cell neoplasm (BPDCN) is an aggressive hematologic cancer that is caused by transformed plasmacytoid dendritic cells that overexpress interleukin-3 receptor subunit alpha (IL3RA or CD123). Tagraxofusp (SL-401) is a CD123-directed cytotoxin consisting of human interleukin-3 fused to truncated diphtheria toxin.In this open ...
Naveen Pemmaraju   +2 more
exaly   +3 more sources

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