Results 141 to 150 of about 332,876 (331)

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Research on the development and performance of new high-brisance emulsion explosives

Scientific Reports
This study developed a novel high-brisance emulsion explosive containing sodium borohydride (NaBH4). The effects of NaBH4 content on the performance of the emulsion explosive were investigated using methods such as brisance, detonation velocity, air ...
M. R. Du, T. D. Xuan, Z. F. Chen, W. W. Li, L. Yuan, B. X. Zheng   +5 more
doaj   +1 more source

Research on the Vertical Bearing Capacity of Concrete-Filled Steel Tube Composite Piles by Mixing Method

Applied Sciences
To address the issues of low shear strength, susceptibility to eccentricity, and alignment difficulties in post-inserted core piles, a new type of steel tube concrete integrated mixing composite pile has been independently developed.
Chaosen Tian, Ping Li, Rongxi Yv, Yixin Li, Bohan Li   +4 more
doaj   +1 more source

Design and Characterization of DX‐Tile DNA Nanostar‐Based Hydrogels

Advanced Science, EarlyView.
In this study, the authors demonstrated that DNA DX‐tile‐based multi‐arm motifs can be used to assemble pure DNA hydrogels, offering greater design flexibility and enhanced control over their mechanical properties and functionalization capabilities compared to single duplex‐based DNA hydrogels.
Dylan V. Scarton, Alessandra B. Coogan, Peter M. Touma, Eray O. Tulun, Katie A. Harrison, Jack Buchen, Richard C. Steiner, Christopher R. Fellin, Hunter G. Mason, Chih‐Hsiang Hu, Sally Farag, Xiaoning Yuan, Shailly Jariwala, Remi Veneziano   +13 more
wiley   +1 more source

Effect of internal phase particle size on properties of site mixed emulsion explosive at plateau environment

Scientific Reports
To study the effect of internal particle size on the microstructure properties and thermal decomposition characteristics of site mixed emulsion explosive at different altitudes. Site mixed emulsion explosive was prepared with different shear rate.
S. D. Xie, X. Y. Cai, H. B. Wu, Q. Wang, Z. R. Guo, Z. Y. Chen, C. S. Ma   +6 more
doaj   +1 more source

An Experimental Investigation on the Dynamic Response of Buried RC Pipes Induced by Falling Impact

Sensors
Unexpected ground impacts can seriously affect the stability and operational safety of buried pipelines. In this paper, a full-scale modeling test of the dynamic response of a buried concrete pipeline under falling rock impact based on dynamic sensor ...
Yingkang Yao, Nan Jiang, Guopeng Lyu, Jinshan Sun, Feng Yang   +4 more
doaj   +1 more source

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

Advanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang, Qingxin Si, Zhiguo Chen, Zhe Yu, Zhan Guo, Lu Wang, Weixi Li, Wangzhen Guo   +7 more
wiley   +1 more source

Experimental study on blasting fracture and stress wave propagation characteristics of hard rock under different boundary conditions

AIP Advances
This investigation systematically explores the impact of heterogeneous boundary constraints on fracture mechanisms and stress wave dynamics in rock specimens with central boreholes subjected to blasting loads.
Nao Lv, JiChao Duan, HaiBo Wang, XiaoHong Zhou, BaoLiang Zhou   +4 more
doaj   +1 more source

Natural Negative Feedback Loops Confer Indica‐Japonica Differentiation for Grain Size Homeostasis in Rice

Advanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li, Meng‐en Wu, Ziqi Qiao, Junkui Huang, Juncheng Zhang, Yang Ding, Junqing Zhu, Jingyue Xu, Yuxin Huang, Wei Li, Xiaomin Su, Yue Ding, Jianwei Zhang, Yibo Li   +13 more
wiley   +1 more source