Results 51 to 60 of about 16,158 (263)

Lateral spreading mitigation in gravity quay walls backfilled with coral sand through electrolysis desaturation treatment

open access: yesScientific Reports
Quay walls constructed on hydraulically filled coral sand deposits face inevitable liquefaction-induced hazards during seismic events. For mitigation, electrolysis method can be employed as an induced partial saturation technique to improve the ...
Junwei Guo   +5 more
doaj   +1 more source

Improved complete ensemble empirical mode decomposition with adaptive noise and composite multiscale permutation entropy for denoising blast vibration signal

open access: yesHeliyon
Monitoring the building blast vibration signal is an efficient way to determine the power of blast vibration hazards. Due to the harsh measurement environment, noise is inevitably introduced into the recorded signals.
Yi-ze Kang   +5 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Dynamic behavior of an adjacent tunnel under blasting and collapse impact loads: a case study of high-rise building blasting demolition

open access: yesAin Shams Engineering Journal
Blasting demolition is widely used for removing high-rise buildings due to its safety and efficiency, but induced vibrations and collapse impacts can damage nearby structures.
Yuqing Xia   +4 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Multi-Dimensional Assessment of Energy Dissipation in Concrete Under Dynamic Impact: Integration of Dynamic Strength Enhancement and Deformation Coordination

open access: yesBuildings
As a widely used structural material in construction, the energy dissipation characteristics of concrete under dynamic impact are crucial for evaluating a structure’s impact resistance and safety performance.
Xiaoyu Jia   +4 more
doaj   +1 more source

Blast Injury [PDF]

open access: yesMilitary Medicine, 2011
Explosions can cause devastating injuries by various wounding mechanisms. Injuries due to the primary pressure wave are rarely life threatening and those that are lethal are uncommon. We reviewed the pathophysiology of blast-related injuries and their implications for management.
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

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