Results 111 to 120 of about 109,750 (256)

Analysis of Human Uniparental Embryonic Stem Cells Reveals New Putative Imprinted Loci

Cell Proliferation, EarlyView.
To identify novel imprinted genes, parthenogenetic, androgenetic and biparental human embryonic stem cells and their differentiated neural progenitors were analysed by methylome and transcriptome profiling. This approach uncovered 12 putative novel imprinted genes, including a clustered region on chromosome 19, expanding the current catalogue of ...
Shay Kinreich, Nissim Benvenisty
wiley   +1 more source

Phosphatase PPP1CC Regulates the First Lineage Segregation by GAS5 in Mouse Preimplantation Embryos

Cell Proliferation, EarlyView.
Subcortical GAS5 directs PPP1CC phosphatase spatiotemporal positioning during mouse morula‐blastocyst transition, controlling YAP dephosphorylation to drive first embryonic lineage specification. ABSTRACT The transcriptional effector of the Hippo signalling pathway, YAP, regulates the first lineage specification in mouse preimplantation embryos ...
Jianwu Wang, Yan Zhang, Laijin Wu, Hongshuang Xie, Guang Yang, Yiwei Zhang, Cheng Huang, Shanyi Chou, Xuehan Li, Zhonghua Liu, Jiaqiang Wang   +10 more
wiley   +1 more source

Clinical factors associated with thaw survival in a cohort of 6167 vitrified-warmed, euploid blastocysts [PDF]

, 2019
Margeaux Oliva, Christine Briton-Jones, Dmitry Gounko, Joseph A. Lee, Alan B. Copperman, L. Sekhon   +5 more
openalex   +1 more source

Switching to testicular sperm after a previous ICSI failure with ejaculated sperm significantly improves blastocyst quality without increasing aneuploidy risk

, 2022
Irene Hervás, María Gil Juliá, Rocío Rivera‐Egea, Ana Navarro‐Gomezlechon, Laura Mossetti, Nicolás Garrido   +5 more
openalex   +2 more sources

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

Equine Veterinary Journal, EarlyView.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez, Alejandro de la Fuente, Kazuki Takahashi, Hugo Monteiro, Mauricio Mendes, Stuart Meyers, Pouya Dini   +6 more
wiley   +1 more source

Impact of FSH-Induced Ovarian Stimulation on Oocyte Recovery and In Vitro Embryo Production in the Red Sindhi Cows. [PDF]

Reprod Domest Anim
ABSTRACT Follicle‐stimulating hormone (FSH) plays an important role in regulating reproductive events, particularly follicular development and oocyte competence acquisition. Some studies using FSH protocols in zebu cattle were performed, but data regarding its application in the Red Sindhi breed are scarce and therefore warranted. In this context, this
Pivato I, Martins GHL, de Faria LC, Bessler HC, Martins CF.   +4 more
europepmc   +2 more sources

Preventing Differentiation Towards Primitive Macrophages in Stem Cells With Down Syndrome

Immunology, EarlyView.
Decreased fetal brain macrophages were previously reported in Ts1Cje mice, a model of Down syndrome (DS). We confirmed the reduction in primitive macrophages, brain macrophage precursors, using Ts1Cje‐derived mouse embryonic stem cells (Ts1Cje‐mESCs) and human induced pluripotent stem cells with trisomy 21 (Tri21‐hiPSCs), with in vivo validation ...
Koki Harada, Keiichi Ishihara, Sayaka Wakayama, Teruhiko Wakayama, Sae Yamamoto, Haruhiko Sago, Shun Shimohama, Satoshi Akiba, Florent Ginhoux, Kazuyuki Takata   +9 more
wiley   +1 more source

Blastocysts originated from oocytes with smooth endoplasmic reticulum aggregates have a reduced euploidy rate: a retrospective cohort study

Frontiers in Endocrinology
Research questionDoes the presence of smooth endoplasmic reticulum aggregates (SERa) in oocytes adversely impact the euploidy rate of subsequent blastocysts?DesignWe performed a retrospective cohort study with 671 young patients (< 38 years ...
Pengcheng Kong, Jiaping Pan, Shanshan Liang, Mingru Yin, Xiaoming Teng   +4 more
doaj   +1 more source

Gene expression analysis in specific cell populations of bovine blastocysts using laser capture microdissection [PDF]

, 2012
Laser capture microdissection (LCM) has become a powerful technique for the isolation of specific cell populations from heterogeneous tissues for gene expression analysis.
Burvenich, Christian, Cornillie, Pieter, De Spiegelaere, Ward, De Spiegeleer, Bart, Goossens, Karen, Peelman, Luc, Stevens, Mieke, Van Soom, Ann   +7 more
core  

Increased apoptosis in bovine blastocysts exposed to high levels of IGF1 is not associated with downregulation of the IGF1 receptor [PDF]

, 2010
Miguel A. Velazquez, D. Hermann, Wilfried A. Kues, Heiner Niemann   +3 more
openalex   +1 more source