Results 71 to 80 of about 89,734 (288)

Asynchronous fate decisions by single cells collectively ensure consistent lineage composition in the mouse blastocyst

open access: yesNature Communications, 2016
Intercellular communication is essential to coordinate the behaviour of individual cells during organismal development. The preimplantation mammalian embryo is a paradigm of tissue self-organization and regulative development; however, the cellular basis
Néstor Saiz   +3 more
semanticscholar   +1 more source

Placental RTN3L‐dependent ER‐Phagy Contributes to Fetal Testicular Dysplasia Upon Environmental Stress

open access: yesAdvanced Science, EarlyView.
Gestational environmental stress activates ER‐phagy by increasing placental Rtn3l mRNA N6‐methyladenosine modification, further inhibiting placental estradiol synthesis and contributing to fetal testicular dysplasia. This study demonstrates the early prevention and treatment of adult male infertility from the perspective of fetal‐derived diseases ...
Ye‐Xin Luo   +17 more
wiley   +1 more source

Large‐Scale Bioprinting of Human Epiblast‐Like Models Featuring Disc‐Shaped Morphogenesis and Gastrulation Events

open access: yesAdvanced Science, EarlyView.
Large‐scale generation of disc‐shaped models mimicking human epiblast layer is achieved by bioprinting of human pluripotent stem cells using a well‐defined biomatrix. The bioactive component and physical confinement from laminin/alginate microgels, combined with the endogenous regulation of the WNT signaling pathway regulated disc‐like morphogenesis ...
Yixue Luo   +11 more
wiley   +1 more source

Should extended blastocyst culture include Day 7?

open access: yesHuman Reproduction, 2018
Extended culture to the blastocyst stage is widely practised, improving embryo selection and promoting single embryo transfer. Selection of useable blastocysts typically occurs on Days 5 and 6 of embryo culture.
E. Hammond, Lynsey M Cree, D. Morbeck
semanticscholar   +1 more source

Green‐to‐red spectral labeling: A novel polysynaptic retrograde tracing strategy in the marker footprint mouse model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
To compensate for the fluorescence loss in rabies virus–derived neuronal tracing tools caused by non‐cytolytic immune clearance (NCLIC) in retrograde tracing, we developed a novel green‐to‐red spectral labeling (GTR) strategy based on the NCLIC phenomenon and developed a novel marker footprints mouse to support the strategy.
Yige Song   +4 more
wiley   +1 more source

Bovine In Vitro Oocyte Maturation and Embryo Production Used as a Model for Testing Endocrine Disrupting Chemicals Eliciting Female Reproductive Toxicity With Diethylstilbestrol as a Showcase Compound

open access: yesFrontiers in Toxicology, 2022
Endocrine disrupting chemicals (EDCs) can interfere with normal hormonal action and regulation. Exposure of women to EDCs has been associated with adverse reproductive health outcomes.
K. Asimaki   +7 more
doaj   +1 more source

Blastocyst-induced changes in the bovine endometrial transcriptome.

open access: yesReproduction, 2018
The objectives of this study were (i) to determine whether blastocyst-induced responses in endometrial explants were detectable after 6- or 24-h co-culture in vitro; (ii) to test if direct contact is required between embryos and the endometrial surface ...
C. Passaro   +7 more
semanticscholar   +1 more source

A polyembryonic blastocyst in the opossum [PDF]

open access: yesThe Anatomical Record, 1917
n ...
Patterson, J. T., Hartman, C. G.
openaire   +3 more sources

Development of node architecture and emergence of molecular organizer characteristics in the pig embryo

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The avian node is the equivalent of the amphibian Spemann's organizer, as indicated by its ability to induce a secondary axis, cellular contribution, and gene expression, whereas the node of the mouse, which displays limited inductive capacities, was suggested to be a part of spatially distributed signaling.
Braah Harmoush   +2 more
wiley   +1 more source

When to Transfer Embryos if There Is Only 1 or 2?

open access: yesLife, 2023
The latest reports suggest that it is better to transfer embryos to the uterus on day five of preimplantation development compared to other days of development, but it is not clear if this stands when there are only one-two embryos obtained in the cycle.
Martin Stimpfel   +3 more
doaj   +1 more source

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