Results 71 to 80 of about 133,185 (340)

Mechanics of mouse blastocyst hatching revealed by a hydrogel-based microdeformation assay

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Blastocyst hatching is crucial for implantation of mammalian embryos and a common failure point during in vitro fertilization (IVF). We have little knowledge of the mechanical basis whereby an embryo hatches out of the zona pellucida.
K. Leonavicius, C. Royer, Chris Preece, B. Davies, J. Biggins, S. Srinivas   +5 more
semanticscholar   +1 more source

Regulation of blastocyst formation

Frontiers in Bioscience, 2001
Preimplantation or pre-attachment development encompasses the "free"-living period of mammalian embryogenesis, which directs development of the zygote through to the blastocyst stage. Blastocyst formation is essential for implantation, establishment of pregnancy and is a principal determinant of embryo quality prior to embryo transfer.
Watson, A J, Barcroft, L C
openaire   +5 more sources

Overall Blastocyst Quality, Trophectoderm Grade, and Inner Cell Mass Grade Predict Pregnancy Outcome in Euploid Blastocyst Transfer Cycles

Chinese Medical Journal, 2018
Background: Despite recent advances that have improved the pregnancy success rates that can be achieved via in vitro fertilization (IVF) therapy, it is not yet clear which blastocyst morphological parameters best predict the outcomes of single blastocyst
Yan-Yu Zhao, Yang Yu, Xiao-Wei Zhang
semanticscholar   +1 more source

Feasibility of artificial intelligence for predicting live birth without aneuploidy from a blastocyst image

Reproductive Medicine and Biology, 2019
Purpose To make the artificial intelligence (AI) classifiers of the image of the blastocyst implanted later in order to predict the probability of achieving live birth.
Yasunari Miyagi, Toshihiro Habara, Rei Hirata, Nobuyoshi Hayashi   +3 more
doaj   +1 more source

Genetic Normalization of Differentiating Aneuploid Human Embryos [PDF]

, 2011
Early embryogenesis involves a series of dynamic processes, many of which are currently not well described or understood. Aneuploidy and aneuploid mosaicism, a mixture of aneuploid and euploid cells within one embryo, in early embryonic development are ...
Andrew Barker, Andrew Benner, Garry Cutting, Kevin Richter, Khanh-Ha Nguyen, Paul Brezina, Raymond Anchan, Ric Ross, William Kearns   +8 more
core   +1 more source

Agouti C57BL/6N embryonic stem cells for mouse genetic resources. [PDF]

, 2009
We report the characterization of a highly germline competent C57BL/6N mouse embryonic stem cell line, JM8. To simplify breeding schemes, the dominant agouti coat color gene was restored in JM8 cells by targeted repair of the C57BL/6 nonagouti mutation ...
Beier, David R, Bradley, Allan, Liang, Qi, Lloyd, Kent C, Moran, Jennifer L, Pettitt, Stephen J, Prosser, Haydn M, Rairdan, Xin Y, Skarnes, William C   +8 more
core   +1 more source

Integration of Bioengineered Tools in Assisted Reproductive Technologies

Advanced Healthcare Materials, EarlyView.
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak, Edith Coonen, Ron van Golde, Erik Vrij   +3 more
wiley   +1 more source

The Effect of Prolonged Culture of Chromosomally Abnormal Human Embryos on The Rate of Diploid Cells [PDF]

International Journal of Fertility and Sterility, 2016
Background A decrease in aneuploidy rate following a prolonged co-culture of human blastocysts has been reported. As co-culture is not routinely used in assisted reproductive technology, the present study aimed to evaluate the effect of the prolonged ...
Masood Bazrgar, Hamid Gourabi, Poopak Eftekhari-Yazdi, Hamed Vazirinasab, Mostafa Fakhri, Fatemeh Hassani, Mohamad Chehrazi, Mojtaba Rezazadeh Valojerdi   +7 more
doaj   +1 more source

Placental deficiency of the (pro)renin receptor ((P)RR) reduces placental development and functional capacity

Frontiers in Cell and Developmental Biology, 2023
The (pro)renin receptor ((P)RR; also known as ATP6AP2) is a multifunctional receptor. The (P)RR activates the tissue renin-angiotensin system (RAS) and is also involved in regulating integral intracellular pathways such as V-ATPase and Wnt/β-catenin ...
Lachlan G. Schofield, Lachlan G. Schofield, Richard G. S. Kahl, Richard G. S. Kahl, Samantha L. Rodrigues, Samantha L. Rodrigues, Joshua J. Fisher, Joshua J. Fisher, Saije K. Endacott, Saije K. Endacott, Sarah J. Delforce, Sarah J. Delforce, Eugenie R. Lumbers, Eugenie R. Lumbers, Jacinta H. Martin, Jacinta H. Martin, Kirsty G. Pringle, Kirsty G. Pringle   +17 more
doaj   +1 more source

In vitro production of bovine embryos derived from individual donors in the Corral® dish [PDF]

, 2017
Background: Since the identity of the embryo is of outmost importance during commercial in vitro embryo production, bovine oocytes and embryos have to be cultured strictly per donor.
A Cebrian-Serrano, Ann Van Soom, C Carolan, C O’Neill, C O’Neill, E Wydooghe, Eline Wydooghe, EM O’Doherty, Erik Mullaart, G Vajta, Hiemke M. Knijn, I Donnay, IGF Goovaerts, J Merton, JF Hasler, JF Hasler, JHF Pontes, JS Merton, K Matsuura, L Ferry, LJ Ding, M Hoelker, M Lane, Maaike Catteeuw, ML Reed, N Gopichandran, NK Khurana, P George, PEJ Bols, PEJ Bols, R Boni, R Roover De, RB Gilchrist, S Spanos, SA Machado, SJ Dai, T Ebner, T Fujita, WG Feng   +38 more
core   +2 more sources