Results 51 to 60 of about 56,325 (220)

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Evaluating the Development and the Expression of Bax, Bcl-2, and ErbB4 Genes following Vitrification of Eight Cell and Blastocyst Embryos [PDF]

Journal of Advanced Biomedical Sciences, 2014
Background & Objective: Vitrification is an effective mean for preserving embryos. During this process, expression of implanting and apoptotic genes changes and can affect the quality of embryos.
Nasrin Majidi, Mansoureh Movahedin, Zohre Mazaheri   +2 more
doaj  

EfficientNet-B0 outperforms other CNNs in image-based five-class embryo grading: a comparative analysis

Journal of Animal Reproduction and Biotechnology
Background: Evaluating embryo quality is crucial for the success of in vitro fertilization procedures. Traditional methods, such as the Gardner grading system, rely on subjective human assessment of morphological features, leading to potential ...
Vincent Jaehyun Shim, Hosup Shim, Sangho Roh   +2 more
doaj   +1 more source

PTPN11 (SHP2) Is Indispensable for Growth Factors and Cytokine Signal Transduction During Bovine Oocyte Maturation and Blastocyst Development

Cells, 2019
This study was aimed to investigate the role of SHP2 (Src-homology-2-containing phosphotyrosine phosphatase) in intricate signaling networks invoked by bovine oocyte to achieve maturation and blastocyst development.
Muhammad Idrees, Lianguang Xu, Seok-Hwan Song, Myeong-Don Joo, Kyeong-Lim Lee, Tahir Muhammad, Marwa El Sheikh, Tabinda Sidrat, Il-Keun Kong   +8 more
doaj   +1 more source

Morphogenesis of the mammalian blastocyst

Molecular and Cellular Endocrinology, 2008
The first 4 days of mouse pre-implantation development are characterized by a period of segmentation, including morphogenetic events that are required for the divergence of embryonic and extra-embryonic lineages. These extra-embryonic tissues are essential for the implantation into the maternal uterus and for the development of the foetus.
Dard, Nicolas, Breuer, Manuel, Maro, Bernard, Louvet-Vallée, Sophie   +3 more
openaire   +4 more sources

Impact of donor mare and stallion identity on the likelihood of pregnancy after transfer of in vitro produced embryos

Equine Veterinary Journal, EarlyView.
Abstract Background The success of in vitro embryo production (IVEP) is influenced by donor mare and stallion. Objectives To determine whether donor mare and stallion influence the pregnancy rate after transfer of in vitro produced (IVP) blastocysts and to identify factors influencing the likelihood of obtaining one or more pregnancies from a single ...
M. Papas, T. A. E. Stout, J. C. M. Vernooij, B. Leemans, L. Arnold, M. M. Beitsma, L. I. Wijnands, M. de Ruijter‐Villani, S. Colleoni, G. Lazzari, C. Galli, A. Claes   +11 more
wiley   +1 more source

The Transcription Factor OVOL2 Represses ID2 and Drives Differentiation of Trophoblast Stem Cells and Placental Development in Mice

Cells, 2020
Trophoblasts are the first cell type to be specified during embryogenesis, and they are essential for placental morphogenesis and function. Trophoblast stem (TS) cells are the progenitor cells for all trophoblast lineages; control of TS cell ...
Mariyan J. Jeyarajah, Gargi Jaju Bhattad, Dendra M. Hillier, Stephen J. Renaud   +3 more
doaj   +1 more source

Time from trophectoderm biopsy to vitrification affects the developmental competence of biopsied blastocysts

Reproductive Medicine and Biology, 2022
Purpose The present study aimed to examine the correlations of the time interval from trophectoderm (TE) biopsy to vitrification with the blastocyst survival rate and blastocyst outgrowth ability.
Tetsuya Miki, Kenji Ezoe, Shizu Kouraba, Kazuki Ohata, Keiichi Kato   +4 more
doaj   +1 more source

Establishment of Salivary Gland Tumors Arising in Salivary Gland‐Specific EWSR1::ATF1 Transgenic Mice

Head &Neck, EarlyView.
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai, Yoshitaka Utsumi, Daisuke Sano, Tatsu Kuwahara, Yoshihiro Aizawa, Takashi Hatano, Hisashi Hasumi, Yutaro Soejima, Tatsukata Kawagoe, Ryosuke Jikuya, Nobuhisa Mizuki, Satoshi Fujii, Toshitaka Nagao, Nobuhiko Oridate   +13 more
wiley   +1 more source