Results 31 to 40 of about 56,325 (220)

Nested Selves: Self‐Organization and Shared Markov Blankets in Prenatal Development in Humans

Topics in Cognitive Science, EarlyView., 2023
Abstract The immune system is a central component of organismic function in humans. This paper addresses self‐organization of biological systems in relation to—and nested within—other biological systems in pregnancy. Pregnancy constitutes a fundamental state for human embodiment and a key step in the evolution and conservation of our species. While not
Anna Ciaunica, Michael Levin, Fernando E. Rosas, Karl Friston   +3 more
wiley   +1 more source

The Open Cryotop System Is Effective for the Simultaneous Vitrification of a Large Number of Porcine Embryos at Different Developmental Stages

Frontiers in Veterinary Science, 2022
The Superfine Open Pulled Straw (SOPS) system is the most commonly used method for vitrification of pig embryos. However, this system only allows the vitrification of four to seven embryos per straw.
Alejandro Gonzalez-Plaza, Alejandro Gonzalez-Plaza, Josep M. Cambra, Josep M. Cambra, Inmaculada Parrilla, Inmaculada Parrilla, Maria A. Gil, Maria A. Gil, Emilio A. Martinez, Emilio A. Martinez, Cristina A. Martinez, Cristina Cuello, Cristina Cuello   +12 more
doaj   +1 more source

Transient Sperm Starvation Improves the Outcome of Assisted Reproductive Technologies

Frontiers in Cell and Developmental Biology, 2019
To become fertile, mammalian sperm must undergo a series of biochemical and physiological changes known as capacitation. These changes involve crosstalk between metabolic and signaling pathways and can be recapitulated in vitro.
Felipe A. Navarrete, Luis Aguila, David Martin-Hidalgo, David Martin-Hidalgo, Darya A. Tourzani, Guillermina M. Luque, Goli Ardestani, Francisco A. Garcia-Vazquez, Francisco A. Garcia-Vazquez, Lonny R. Levin, Jochen Buck, Alberto Darszon, Mariano G. Buffone, Jesse Mager, Rafael A. Fissore, Ana M. Salicioni, María G. Gervasi, Pablo E. Visconti   +17 more
doaj   +1 more source

Future Perspectives of POSEIDON Stratification for Clinical Practice and Research

Frontiers in Endocrinology, 2019
A total of 50% of patients undergoing IVF treatment has previously been estimated to fulfill the POSEIDON classification criteria; importantly, although the reproductive prognosis differs between patients, POSEIDON patients share the same characteristic ...
Peter Humaidan, Peter Humaidan, Antonio La Marca, Carlo Alviggi, Carlo Alviggi, Sandro C. Esteves, Sandro C. Esteves, Sandro C. Esteves, Sandro C. Esteves, Thor Haahr, Thor Haahr   +10 more
doaj   +1 more source

Can Blastocyst Morphometrics Be a Non-invasive Predictive Marker for Clinical Pregnancy in In vitro Fertilisation Cycles? A Prospective Cohort Study

Journal of Human Reproductive Sciences
Background: Blastocyst diameter is a key morphometric indicator used to predict implantation. Some studies suggest, well-expanded blastocysts generally demonstrate significantly higher clinical pregnancy and live birth rates compared to smaller embryos ...
Neeta Singh, Supriya Kumari, Monika Saini, Maroof Ahmad Khan   +3 more
doaj   +1 more source

Synchrony of the first division as an index of the blastocyst formation rate during embryonic development

Reproductive Medicine and Biology, 2018
Purpose To devise an uninvasive selection system for human embryos with high developmental potential after a single oocyte retrieval cycle by comparing the in vitro and in vivo effectiveness of first division synchrony against subsequent embryonic ...
Yamato Mizobe, Makoto Tokunaga, Naoto Oya, Reiko Iwakiri, Naomi Yoshida, Yumi Sato, Nanase Onoue, Yuji Ezono   +7 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Efficient derivation of embryonic stem cells and primordial germ cell-like cells in cattle

The Journal of Reproduction and Development
The induction of the germ cell lineage from pluripotent stem cells (in vitro gametogenesis) will help understand the mechanisms underlying germ cell differentiation and provide an alternative source of gametes for reproduction.
Atsushi SHIRASAWA, Masafumi HAYASHI, Mayumi SHONO, Atsushi IDETA, Takashi YOSHINO, Katsuhiko HAYASHI   +5 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source