Spontaneous Pneumomediastinum and Bilateral Pneumothoraces in a Patient with Bleomycin-Induced Pneumonitis [PDF]
European Journal of Case Reports in Internal Medicine, 2017 Bleomycin lung toxicity is well established and can manifest as bleomycin-induced pneumonitis, but pneumomediastinum and pneumothorax are very rare complications.
Matthieu Barras, Marc Uhlmann
doaj +5 more sources
Mitochondria-target ubiquinone attenuates bleomycin-induced pulmonary fibrosis [PDF]
Frontiers in PharmacologyBackgroundPulmonary fibrosis arises from various etiologies, often associated with elevated levels of reactive oxygen species (ROS) stress and activation of pro-fibrotic signaling pathways. The chemotherapeutic drug bleomycin has been shown to exacerbate
Ying Jiang +10 more
doaj +2 more sources
Pharmaceutics, 2021 The plasma concentration profile of bleomycin in the distribution phase of patients younger than 65 years is needed to determine the suitable time interval for efficient application of electric pulses during electrochemotherapy.
Ales Groselj +9 more
doaj +1 more source
Photochemical Internalization with Fimaporfin: Enhanced Bleomycin Treatment for Head and Neck Cancer
Pharmaceutics, 2023 Head and neck squamous cell carcinoma (HNSCC) still represents the world’s sixth most common tumor entity, with increasing incidence. The reachability of light makes HNSCC suitable for light-based therapies such as Photochemical Internalization (PCI ...
Paula Enzian, Ramtin Rahmanzadeh
doaj +1 more source
Bleomycin-Induced Pulmonary Toxicity in Cancer Patients Treated at Tertiary Care Hospital
Pakistan Armed Forces Medical Journal, 2023 Objective: To report the frequency of Bleomycin-induced pulmonary toxicity in cancer patients treated with chemotherapy regimens containing Bleomycin at Combined Military Hospital, Rawalpindi Pakistan. Study Design: Case series.
Aamira Ali +5 more
doaj +1 more source
Nintedanib treatment for bleomycin-induced lung injury - First report
Respiratory Medicine Case Reports, 2023 Although the antineoplastic agent bleomycin is known for more than 50 years, its exact pharmacological and side-effect mechanisms remain incompletely understood.
Dina Rnjak +6 more
doaj +1 more source
Clinical Dermatology Review, 2023 Background: Treating of recalcitrant viral verrucae either individually or in combination is inconvenient and frustrating both for patients and treating physician. There is no treatment, which is 100% effective for warts.
Prasoon Sachan +4 more
doaj +1 more source
Administration of bleomycin via the oropharyngeal aspiration route leads to sustained lung fibrosis in mice and rats as quantified by UTE-MRI and histology. [PDF]
PLoS ONE, 2013 Pulmonary fibrosis can be experimentally induced in small rodents by bleomycin. The antibiotic is usually administered via the intratracheal or intranasal routes.
Christine Egger +10 more
doaj +1 more source
Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis [PDF]
, 2012 Idiopathic pulmonary fibrosis (IPF) is a fatal disease that is unresponsive to current therapies and characterized by excessive collagen deposition and subsequent fibrosis.
Anderson, G.P. +19 more
core +2 more sources
Amelioration of bleomycin-induced lung fibrosis in hamsters by dietary supplementation with taurine and niacin: biochemical mechanisms. [PDF]
, 1994 Interstitial pulmonary fibrosis induced by intratracheal instillation of bleomycin (BL) involves an excess production of reactive oxygen species, unavailability of adequate levels of NAD and ATP to repair the injured pulmonary epithelium, and an ...
Chandler DB +34 more
core +2 more sources