Results 171 to 180 of about 53,368 (224)
Some of the next articles are maybe not open access.
Mutation Research - Reviews in Genetic Toxicology, 1991
Lawrence F Povirk, L F Povirk
exaly +3 more sources
Lawrence F Povirk, L F Povirk
exaly +3 more sources
Otolaryngology–Head and Neck Surgery, 1979
Chairman's Comments: The Otolaryngology Drug Capsule, a popular part of the Academy's publication, the Perceived, is being transferred to otolaryngology and head and neck surgery at the request of the editors of the Journal. This capsule is sponsored by the Committee on Drugs—Otolaryngology and represents a continuing effort by its membership.In this ...
E P, Lester, G J, Matz
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Chairman's Comments: The Otolaryngology Drug Capsule, a popular part of the Academy's publication, the Perceived, is being transferred to otolaryngology and head and neck surgery at the request of the editors of the Journal. This capsule is sponsored by the Committee on Drugs—Otolaryngology and represents a continuing effort by its membership.In this ...
E P, Lester, G J, Matz
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Oncology, 2009
Since the original observation and description of the various forms of Bleomycin (BLM), numerous articles have appeared dealing with the activity on mammalian cells and its possible clinical use. The present review on this very important compound, although not very comprehensive, deals with the important characteristics; such as the action of DNA and ...
N P, Bishun, N S, Smith, D C, Williams
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Since the original observation and description of the various forms of Bleomycin (BLM), numerous articles have appeared dealing with the activity on mammalian cells and its possible clinical use. The present review on this very important compound, although not very comprehensive, deals with the important characteristics; such as the action of DNA and ...
N P, Bishun, N S, Smith, D C, Williams
openaire +2 more sources
ORL, 2010
50 patients with advanced malignancy treated with bleomycin were assessed for taste abnormality. 5 (10%) cases were found to have some degree of taste impairment. Gustation sense returned to normal within 10–12 weeks following discontinuation of bleomycin therapy.
N K, Soni, P, Chatterji
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50 patients with advanced malignancy treated with bleomycin were assessed for taste abnormality. 5 (10%) cases were found to have some degree of taste impairment. Gustation sense returned to normal within 10–12 weeks following discontinuation of bleomycin therapy.
N K, Soni, P, Chatterji
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Pharmacokinetics of bleomycin in man
Cancer Chemotherapy and Pharmacology, 1979Of all the bleomycin-containing radiopharmaceuticals, bleomycin 57Co has proven the most useful whole-body tumor-imaging agent. We have studied its in vitro physicochemical properties and in vivo disposition in animals and man to optimize its use as a scanning agent.
D S, Alberts +8 more
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Metabolic inactivation of bleomycin analogs by bleomycin hydrolase
Pharmacology & Therapeutics, 1988La bleomycine est inactivee in vivo et in vitro par une enzyme appelee bleomycine hydrolase, et transformee en deaminobleomycine a activite biologique reduite. Les caracteristiques de cette enzyme (localisation tissulaire, poids moleculaire…) et ses parametres cinetiques, sont ...
S M, Sebti, J S, Lazo
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Studies on Bleomycin-DNA and Bleomycin-Iron Interactions
Journal of Biomolecular Structure and Dynamics, 1983The bleomycins, a group of antitumor antibiotics (Figure 1), cause the degradation of DNA by a process requiring iron(II) and dioxygen (1,2). DNA degradation appears to involve two steps: association of the drug with the nucleic acid and degradation of the DNA.
T T, Sakai +6 more
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Cryogenic Photolysis of Activated Bleomycin to Ferric Bleomycin
The Journal of Physical Chemistry B, 2006Activated bleomycin (ABLM) is a drug--Fe(III)-hydroperoxide complex kinetically competent in DNA attack (via H4' abstraction). This intermediate is relatively stable, but its spontaneous conversion to ferric bleomycin (Fe(III).BLM) is poorly characterized because no observable intermediate product accumulates.
Richard M, Burger +3 more
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Cancer Chemotherapy and Pharmacology, 1984
Experimental and clinical evidence indicates that bleomycin by continuous infusion is superior to intermittent administration. Continuous infusion is less convenient, however. It has been suggested that a suspension of bleomycin in sesame oil, given by IM injection, simulates a continuous infusion.
M L, Slevin +5 more
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Experimental and clinical evidence indicates that bleomycin by continuous infusion is superior to intermittent administration. Continuous infusion is less convenient, however. It has been suggested that a suspension of bleomycin in sesame oil, given by IM injection, simulates a continuous infusion.
M L, Slevin +5 more
openaire +2 more sources