Results 51 to 60 of about 245,917 (306)

Control, elimination, and eradication of river blindness: scenarios, timelines, and ivermectin treatment needs in Africa [PDF]

, 2015
River blindness (onchocerciasis) causes severe itching, skin lesions, and vision impairment including blindness. More than 99% of all current cases are found in sub-Saharan Africa.
Remme, JHF, Roungou, Jean-Baptiste, Peter Steinmann, Steinmann, P. (Peter), Young Eun Kim (117995), Peter Steinmann (92572), Wilma A Stolk, Roungou, J.-B. (Jean-Baptiste), Roungou, Jean Baptiste, Kim, YE, Stolk, Wilma, Kim, Young Eun, Stolk, W.A. (Wilma), Tediosi, F. (Fabrizio), Stolk, Wilma; id_orcid, Fabrizio Tediosi (247282), Tediosi, F, Steinmann, P, Young Eun Kim, Jean-Baptiste Roungou (720638), Jan H. F. Remme (261767), Steinmann, Peter, Wilma A. Stolk (107546), Roungou, JB, Stolk, Wilma A., Tediosi, Fabrizio, Remme, Jan H. F., Kim, Y.E. (Young Eun), Jean-Baptiste Roungou, Fabrizio Tediosi, Remme, J.H.F. (Jan), Jan H F Remme   +31 more
core   +3 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Reversal learning is influenced by cognitive flexibility and develops throughout early adolescence

npj Science of Learning
Learning behavioural responses and adapting them based on feedback is crucial from a young age, continuing to develop into young adulthood. This study examines the development trajectory and contributing factors from childhood to adulthood using a ...
Christoph Bamberg, Sarah Weigelt, Klara Hagelweide   +2 more
doaj   +1 more source

Application of the ex-Gaussian function to the effect of the word blindness suggestion on Stroop task performance suggests no word blindness. [PDF]

, 2013
The aim of the present paper was to apply the ex-Gaussian function to data reported by Parris et al. (2012) given its utility in studies involving the Stroop task. Parris et al.
Benjamin Andrew Parris, Zoltan Dienes (4460371), Zoltan Dienes, Hodgson, Timothy Lewis, Benjamin A. Parris, Timothy L Hodgson (16154033), Timothy L. Hodgson, Parris, Benjamin, Zoltan eDienes, Benjamin A Parris (11171354), Dienes, Z., Timothy Lewis Hodgson   +11 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Novel Compound Heterozygous Variations in MPDZ Gene Caused Isolated Bilateral Macular Coloboma in a Chinese Family

Cells, 2022
Macular coloboma (MC) is a rare congenital retinochoroidal defect characterized by lesions of different sizes in the macular region. The pathological mechanism underlying congenital MC is unknown.
Shuang Zhang, Fangxia Zhang, Juan Wang, Shangying Yang, Yinghua Ren, Xue Rui, Xiaobo Xia, Xunlun Sheng   +7 more
doaj   +1 more source

Magnitude and Causes of Visual Impairment and Blindness Among Children Attending Paediatric Eye Clinic at Muhimbili National Hospital, 2010 [PDF]

, 2011
The number of blind years resulting from blindness in children is alarmingly high. Blindness in children can have a significant impact on their performance at school as well as their social interaction and future employment as visually impaired children ...
Mhina, Celina, Mhina, Cellina
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The Fate of RPE Cells Following hESC-RPE Patch Transplantation in Haemorrhagic Wet AMD: Pigmentation, Extension of Pigmentation, Thickness of Transplant, Assessment for Proliferation and Visual Function—A 5 Year-Follow Up

Diagnostics
(1) Background: We reviewed a stem cell-derived therapeutic strategy for advanced neovascular age-related macular degeneration (nAMD) using a human embryonic stem cell-derived retinal pigment epithelium (hESC-RPE) monolayer delivered on a coated ...
Lyndon da Cruz, Taha Soomro, Odysseas Georgiadis, Britta Nommiste, Mandeep S. Sagoo, Peter Coffey   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source