Results 91 to 100 of about 10,649 (222)

Effects of a leave‐on product on the strength of the dermoepidermal junction: An exploratory, intraindividual, randomized controlled trial in older adults with dry skin

Health Science Reports
Background and Aims Skin aging is associated with dry skin and a decrease of the strength of the dermoepidermal adhesion, which increases the risk for lacerations (skin tears).
Ruhul Amin, Fiorenza Rancan, Kathrin Hillmann, Ulrike Blume‐Peytavi, Annika Vogt, Jan Kottner   +5 more
doaj   +1 more source

Matrix metalloproteinases -8 and -9 and tissue inhibitor of metalloproteinase-1 in burn patients. A prospective observational study.

PLoS ONE, 2015
IntroductionMatrix metalloproteinases (MMPs) -8 and -9 are released from neutrophils in acute inflammation and may contribute to permeability changes in burn injury.
Johanna Hästbacka, Filip Fredén, Maarit Hult, Maria Bergquist, Erika Wilkman, Jyrki Vuola, Timo Sorsa, Taina Tervahartiala, Fredrik Huss   +8 more
doaj   +1 more source

OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders

Journal of the European Academy of Dermatology and Venereology, EarlyView.
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta, Julia Steriopoulos, Vasiliki Economopoulos, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Darier disease—A review highlighting new insights from the Darier Disease International Task Force

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review provides a global, clinically focused overview of DD, detailing cutaneous and extracutaneous manifestations, disease classification and severity scoring. It emphasizes early recognition, multidisciplinary management and practical guidance for dermatologists to apply evidence‐based care in diverse skin phototypes. Abstract Darier disease (DD)
Sofia Labbouz, Alain Hovnanian, Grace Xiong, Dedee Frances Murrell, Simon M. Mueller, Khaled Ezzedine, Nessa Aghazadeh Mohandesi, Ahmed Salem Aldhaheri, Nissim Asayag, Eulalia Baselga, Chen Nadler, Keith Choate, Chia‐Yu Chu, John Robert Edminister, Emmanuella Guenova, Melis Gönülal, Antoni Gostynski, Ankan Gupta, Lalit Kumar Gupta, Juliette Mazereeuw‐Hautier, Wolfram Hoetzenecker, Peter Itin, Marek Jankowski, Akiharu Kubo, Haur Yueh Lee, Julia Scott Lehman, Anfisa Lepekhova, Márta Medvecz, Jemima E. Mellerio, Verena Moosbrugger‐Martinz, Amy S. Paller, Dóra Plázár, Amadeu José Rodrigues Queiróz, Josep Riera‐Monroig, Ralph Rosa, Matthias Schmuth, Maella Severino Freire, Itzhak Shabat, Jonathan Shapiro, Cory L. Simpson, Diego Soto‐García, Alexander J. Stratigos, Gianluca Abel Tadini, Takuya Takeichi, Kaushal K. Verma, Jakob D. Wikström, Alexander Zink, Michael Ziv, Alexander Navarini, Roni Pircha Dodiuk‐Gad   +49 more
wiley   +1 more source

The Imbalance Between Metalloproteinases and Their Tissue Inhibitors Is Involved in the Pathogenesis of Dermatitis Herpetiformis

Mediators of Inflammation, 2005
Dermatitis herpetiformis (DH) is a subepidermal autoimmune disease characterized by skin and intestinal lesions consistent with coeliac disease. There are also some data that metalloproteinases (MMPs) are involved in the development of skin lesions in DH,
Agnieszka Zebrowska, Joanna Narbutt, Anna Sysa-Jedrzejowska, Jozef Kobos, Elzbieta Waszczykowska   +4 more
doaj   +1 more source

Tocilizumab for severe and refractory mucous membrane pemphigoid

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Elevated IL‐6 levels identified in mucous membrane pemphigoid support IL‐6 blockade, with tocilizumab demonstrating clinical benefit in nine patients with severe and refractory mucous membrane pemphigoid. Abstract Background Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease involving mucous membranes with a potentially ...
Billal Tedbirt, Maud Maho‐Vaillant, Julie Gueudry, Marie‐Laure Golinski, Marion Marcaillou, Blanche Bergeret, Guillaume Chambon, Pierre Bouchetemble, Soumeya Bekri, Abdellah Tebani, Hervé Maillard, Cécile Morice, Anais Vautier, Edgar‐Pierre Libert, Christelle Le Roux‐Villet, Marion Carrette, Olivier Boyer, Vivien Hébert, Sébastien Calbo, André Gillibert, Pascal Joly   +20 more
wiley   +1 more source

Antimicrobial prescribing guidelines for feedlot cattle

Australian Veterinary Journal, EarlyView.
P Cusack, T Batterham, SW Page, GF Browning, JM Norris   +4 more
wiley   +1 more source

Development of Multidisciplinary Consensus‐Informed Guidance for the Management of Paediatric Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis Among Clinicians From Australasian Tertiary Referral Hospitals

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Paediatric Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare, severe mucocutaneous reaction requiring coordinated multidisciplinary care. Existing guidelines provide evidence‐based recommendations, but implementation across tertiary paediatric hospitals requires practical consensus on local resources.
Patrick David Mahar, Thomas Lee, David Orchard, Amy Gray, Laura Scardamaglia, Susan Robertson, Monique Bertinetti, Warwick Teague, Danielle Nizzero, Claire Grills, Ryan Toholka, Danni Bao, Julian Kelly, Joanne Grindlay, Thomas Rozen, Mark Oliver, Nicole Alexander, Ashan Fernando, Anu Matthew, Kiri Chan, Sonia R. Grover, Emma McDonald, Li‐Chuen Wong, Marius Rademaker, Diana Purvis, Katherine Dear, Stephanie Weston, Vanessa Morgan, Anne Halbert, Orli Wargon, Gayle Fischer, Erin Mewton, Emma King   +32 more
wiley   +1 more source

Nanoscale space weathering features in mature lunar soil revealed by TEM and APT

Meteoritics &Planetary Science, EarlyView.
Abstract Space weathering significantly alters the optical, chemical, and structural properties of lunar regolith at micro‐ and nanoscales; yet detailed nanoscale variability within individual soils remains underexplored. Here we apply transmission electron microscopy (TEM) and atom probe tomography to four mineral grains (olivine, ilmenite, and two ...
Jennika Greer, Alexander M. Kling, Luke Daly, Dieter Isheim, David N. Seidman, Michelle S. Thompson, Philipp R. Heck   +6 more
wiley   +1 more source

A Meta‐Analysis Reveals That the Protective Role of Silicon in Grasses Against Fungal Pathogens Depends on Infection Mechanism

Plant, Cell &Environment, EarlyView.
ABSTRACT Pathogen infection drives plant community structure and constrains global agricultural productivity. Silicon (Si) improves resistance to abiotic and herbivory stress, particularly in grasses, but relatively little attention has addressed Si‐mediated resistance to pathogens, nor has it tested how this varies according to the type of plant and ...
Sarah J. Thorne, Julia Cooke, Susan E. Hartley   +2 more
wiley   +1 more source