Results 81 to 90 of about 10,649 (222)

Pilot study investigating BP-180 in extracellular vesicles derived from blister fluid of bullous pemphigoid patients. [PDF]

Arch Dermatol Res, 2023
Gasparini G, Tasso R, Palamà MEF, Ciferri MC, Gentili C, Di Zenzo G, Provini A, Salemme A, Quarto R, Parodi A, Cozzani E.   +10 more
europepmc   +1 more source

Recovery of Pure PVC From Pharmaceutical Composite Packaging via Dissolution‐Based Recycling

Journal of Vinyl and Additive Technology, EarlyView.
Closed‐loop pathway for pharmaceutical blister waste via selective dissolution‐based recycling (DBR) enables separation of PVDC and aluminum, PVC recovery and reprocessing into films with 30 phr recycled content, and validation for thermoforming applications.
Martin Schlummer, Swetlana Wagner, Franziska Ludwig, Michael Nedelcu, Oliver Paillerau, Thomas Hülsmann   +5 more
wiley   +1 more source

Eosinophil Cationic Protein (ECP), a predictive marker of bullous pemphigoid severity and outcome

Scientific Reports, 2017
Bullous Pemphigoid (BP) is an inflammatory rare autoimmune bullous dermatosis, which outcome cannot be predicted through clinical investigations. Eosinophils are the main immune infiltrated cells in BP.
Delphine Giusti, Gregory Gatouillat, Sébastien Le Jan, Julie Plée, Philippe Bernard, Frank Antonicelli, Bach Nga Pham   +6 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Cyclophosphamide is associated with long‐term treatment‐free remission in patients with pemphigus

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objective Pemphigus treatment has seen significant advancements, yet long‐term remission remains a challenge. Comparative data on the long‐term effectiveness of available therapies are limited. We compared 10‐year relapse rates in pemphigus patients treated with azathioprine or cyclophosphamide plus high‐dose IV corticosteroids ...
Bettina Santler, Simon Lüdtke, Lena Dietze, Marie Schiffmann, Dominik Straube, Jan Ehrchen   +5 more
wiley   +1 more source

IL-23/IL-17 Axis Activates IL-1β-Associated Inflammasome in Macrophages and Generates an Auto-Inflammatory Response in a Subgroup of Patients With Bullous Pemphigoid

Frontiers in Immunology, 2019
Bullous Pemphigoid (BP) is a skin autoimmune blistering disease characterized by immune-mediated degradation of the dermo-epidermal junction and release of a large number of inflammatory cytokines. Interleukin-1β (IL-1β) is a pleiotropic pro-inflammatory
Sébastien Le Jan, Céline Muller, Julie Plee, Anne Durlach, Philippe Bernard, Frank Antonicelli, Frank Antonicelli   +6 more
doaj   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Blister fluid as a cellular input for <i>ex vivo</i> diagnostics in drug-induced severe cutaneous adverse reactions improves sensitivity and explores immunopathogenesis. [PDF]

J Allergy Clin Immunol Glob, 2022
Awad A, Mouhtouris E, Nguyen-Robertson CV, Holmes N, Chua KYL, Copaescu A, James F, Goh MS, Aung AK, Godfrey DI, Philips EJ, Gibson A, Almeida CF, Trubiano JA, Australian Registry of Severe Cutaneous Adverse Reactions (AUS-SCAR).   +14 more
europepmc   +1 more source

Predicting habitat suitability of selected Meloidae species and future potential refugia: A case study from inner Western Anatolia

Insect Conservation and Diversity, EarlyView.
Consensus habitat‐suitability maps identify current hotspots of species richness across the Inner Western Anatolian mountain systems. Late‐century projections (2081–2100) under SSP2‐4.5 and SSP5‐8.5 show range shifts and changing richness patterns, intensifying at higher elevations.
Muhammed Arif Demir, Mahmut Kabalak
wiley   +1 more source

Incidence of P200 pemphigoid: A nationwide study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The anti‐LAMB4 cell‐based immunoassay is a new serological technique that is far superior to dermal immunoblotting for detecting autoantibodies directed against the P200 protein. This method allows a re‐evaluation of the incidence of P200 pemphigoid, which appears to be considerably more frequent than epidermolysis bullosa acquisita.
Fabienne Jouen, Marion Carrette, Marie‐Laure Golinski, Maud Maho‐Vaillant, Alexis Lefebvre, André Gillibert, Pascal Joly, Vivien Hébert   +7 more
wiley   +1 more source