Results 91 to 100 of about 724,525 (268)
Spot It! and balanced block designs: keys to better debate architecture for a plethora of candidates in presidential primaries? [PDF]
J Appl Stat, 2023 Potthoff RF.
europepmc +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Group Divisible Designs with Two Associate Classes and 𝜆2=1
International Journal of Mathematics and Mathematical Sciences, 2011 The original classiffcation of PBIBDs defined group divisible designs GDD(𝑣=𝑣1+𝑣2+⋯+𝑣𝑔,𝑔,𝑘,𝜆1,𝜆2) with 𝜆1≠0. In this paper, we prove that the necessary conditions are suffcient for the existence of the group divisible designs with two groups of unequal ...
Nittiya Pabhapote, Narong Punnim
doaj +1 more source
Combinatorial Designs with Two Singular Values II. Partial Geometric Designs [PDF]
In this and an earlier paper [17] we study combinatorial designs whose incidence matrix has two distinct singular values.These generalize (v, k, ë) designs, and include uniform multiplicative designs and partial geometric designs.Here we study the latter,
Dam, E.R. van, Spence, E.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Cyclic Polygonal Designs with Block size 3 and Joint Distance 3 [PDF]
Pakistan Journal of Commerce and Social Sciences, 2011 polygons, are useful in survey sampling in terms of balanced sampling plans excluding contiguous units (BSECs) and balanced sampling plans excluding adjacent units (BSAs) when neighboring units in a population provide similar information.
M. H. Tahir (Corresponding author) +2 more
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Deterministic Construction of Measurement Matrices Based on Bose Balanced Incomplete Block Designs
IEEE Access, 2018 Compressed sensing is a novel information collection theory. Compared with the Nyquist sampling theorem, compressed sensing can obtain all the information of a signal with very few samples.
Liu Haiqiang +4 more
doaj +1 more source