99m-Tc MDP Bone Scan Image Enhancement using Pipeline Application of Dynamic Stochastic Resonance Algorithm and Block-Matching 3D Filter. [PDF]
Indian J Nucl Med, 2023 Pandey AK +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
A new HSI denoising method via interpolated block matching 3D and guided filter. [PDF]
PeerJ, 2021 Xu P, Chen B, Zhang J, Xue L, Zhu L.
europepmc +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Preprocessing Pipelines including Block-Matching Convolutional Neural Network for Image Denoising to Robustify Deep Reidentification against Evasion Attacks. [PDF]
Entropy (Basel), 2021 Pawlicki M, Choraś RS.
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Fully Polarimetric SAR Image Filtering by Combining Block Matching and Lee Filter
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingSpeckle filtering is a key preprocessing approach for the applications of polarimetric synthetic aperture radar (PolSAR) data. Most current PolSAR filtering algorithms can hardly get good balance in suppressing speckle and retaining image details.
Guisheng Zhao, Shengyuan Zhu, Yinglei Wu
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Towards Automated Eye Diagnosis: An Improved Retinal Vessel Segmentation Framework Using Ensemble Block Matching 3D Filter. [PDF]
Diagnostics (Basel), 2021 Naveed K +5 more
europepmc +1 more source