Results 71 to 80 of about 3,209,428 (350)

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

An efficient algorithm for the blocked pattern matching problem [PDF]

Bioinformatics, 2014
Motivation: Tandem mass spectrometry (MS) has become the method of choice for protein identification and quantification. In the era of big data biology, tandem mass spectra are often searched against huge protein databases generated from genomes or RNA-Seq data for peptide identification. However, most existing tools for MS-based peptide identification
Deng, Fei, Wang, Lusheng, Liu, Xiaowen
openaire   +2 more sources

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Influence of Block Geometry Configuration on Multi-Image Dense Matching

Remote Sensing, 2022
Digital photogrammetry is a widespread surveying technique in different fields of application due to its flexibility, versatility and cost-effectiveness.
Nazarena Bruno, Riccardo Roncella, Fabrizio Diotri, Klaus Thoeni, Anna Giacomini   +4 more
doaj   +1 more source

Matched bipartite block model with covariates

, 2017
Community detection or clustering is a fundamental task in the analysis of network data. Many real networks have a bipartite structure which makes community detection challenging. In this paper, we consider a model which allows for matched communities in the bipartite setting, in addition to node covariates with information about the matching.
Razaee, Zahra S, Amini, Arash A, Li, Jingyi Jessica   +2 more
openaire   +3 more sources

ORIENTATION OF UAV IMAGE BLOCKS BY SURFACE MATCHING [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
Abstract. Topographic maps are produced in Portugal by the Army Geospatial Data Centre, based on a geographical database collected from aerial photography in resolutions from 0.30 to 0.50 m. Each map sheet is revised with an update interval of 10 years or more. Many changes, such as new roads or power lines, would be possible to update with much higher
J. A. Gonçalves, N. Jordão, N. Jordão, A. Pinhal   +3 more
openaire   +4 more sources

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

CDP-MVS: Forest Multi-View Reconstruction with Enhanced Confidence-Guided Dynamic Domain Propagation

Remote Sensing
Using multi-view images of forest plots to reconstruct dense point clouds and extract individual tree parameters enables rapid, high-precision, and cost-effective forest plot surveys.
Zitian Liu, Zhao Chen, Xiaoli Zhang, Shihan Cheng   +3 more
doaj   +1 more source

New Selective Block Matching Searching Algorithm Based on Block Discriminator Values For Motion Estimation [PDF]

Engineering and Technology Journal, 2015
In this paper, a new, fast and efficient selective block matching algorithm based on block discriminator values is suggested. The searching scheme consists of three stages: block discriminator values calculations, open full window then cascaded selection
Bushra A. Sultan, Nidaa F. Hassan
doaj   +1 more source