Results 111 to 120 of about 5,909,835 (371)
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Block-Wise Two-Dimensional Maximum Margin Criterion for Face Recognition
The Scientific World Journal, 2014 Maximum margin criterion (MMC) is a well-known method for feature extraction and dimensionality reduction. However, MMC is based on vector data and fails to exploit local characteristics of image data.
Xiao-Zhang Liu, Guan Yang
doaj +1 more source
Efficient Block Approximate Matrix Multiplication
, 2023 Randomized matrix algorithms have had significant recent impact on numerical linear algebra. One especially powerful class of methods are algorithms for approximate matrix multiplication based on sampling. Such methods typically sample individual matrix rows and columns using carefully chosen importance sampling probabilities. However, due to practical
Yang, Chuhan, Musco, Christopher
openaire +2 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Reduced order feedback control equations for linear time and frequency domain analysis [PDF]
An algorithm was developed which can be used to obtain the equations. In a more general context, the algorithm computes a real nonsingular similarity transformation matrix which reduces a real nonsymmetric matrix to block diagonal form, each block of ...
Frisch, H. P.
core +1 more source
Blocking Techniques for Sparse Matrix Multiplication on Tensor Accelerators [PDF]
, 2022 Paolo Sylos Labini +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Binary Tree Block Encoding of Classical Matrix
IEEE Transactions on Quantum EngineeringState preparation and block encoding are essential subroutines in quantum computing. The former provides basic encoding of quantum states, while the latter transforms classical data into a matrix representation within a quantum circuit.
Zexian Li +3 more
doaj +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source