Results 51 to 60 of about 501,341 (265)
Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte +5 more
wiley +1 more source
ABSTRACT Background Acute lymphoblastic leukaemia (ALL) is one of the most treatable forms of paediatric cancer; however, there is a substantial burden of treatment‐related toxicities (TRTs). In addition, the long‐term changes in children's health‐related quality of life (HRQoL) due to toxic treatments are not well understood.
Clare Ghows +19 more
wiley +1 more source
The Occipital Nerves Applied Strain Test to Support Occipital Neuralgia Diagnosis
Introduction Occipital neuralgia (ON) is a disabling cephalalgia form with demanding diagnostic workflow. We report the description and reliability analyses of the occipital nerves-applied strain (ONAS) test for occipital neuralgia (ON) early-stage ...
Boaz G. Samolsky Dekel +3 more
doaj +1 more source
ABSTRACT Background General pediatricians often evaluate hematologic and oncologic presentations before subspecialty consultation, yet the 2025 Accreditation Council for Graduate Medical Education (ACGME) pediatric requirements reduce inpatient pediatric hematology/oncology (PHO) time, raising questions about resident readiness.
Colburn Yu, Rohini Jain
wiley +1 more source
Molecular Determinants of hERG Channel Block by Terfenadine and Cisapride
Block of cardiac hERG K+ channels by the antihistamine terfenadine and the prokinetic agent cisapride is associated with prolonged ventricular repolarization and an increased risk of ventricular arrhythmia.
Kaichiro Kamiya +4 more
doaj +1 more source
Block sensitivity of minterm-transitive functions
Boolean functions with symmetry properties are interesting from a complexity theory perspective; extensive research has shown that these functions, if nonconstant, must have high `complexity' according to various measures. In recent work of this type, Sun gave bounds on the block sensitivity of nonconstant Boolean functions invariant under a transitive
openaire +2 more sources
Communication lower bounds via critical block sensitivity [PDF]
33 pages, 6 ...
Mika Göös, Toniann Pitassi
openaire +4 more sources
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean +7 more
wiley +1 more source
Sensitivity-Guided Mixed-Precision Quantization-Aware Training for Large Language Models
Efficient deployment of large language models (LLMs) requires accuracy-preserving compression, yet prior uniform-precision quantization-aware training (QAT) methods ignore variation in layer sensitivity and incur up to 2.6 pp accuracy degradation at 3 ...
Gautam Krishna Mooppil +3 more
doaj +1 more source

