Results 61 to 70 of about 1,026,952 (386)

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

FEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta, Agnieszka Katarzyna Maciola, Tania Baccega, Giulia Pasqual   +3 more
wiley   +1 more source

A COMPARATIVE ANALYSIS WAS CONDUCTED TO ASSESS THE IMPACT OF EPIDURAL ADMINISTRATION OF LEVOBUPIVACAINE 0.5% AT A VOLUME OF 20 ML AND ROPIVACAINE 0.75% AT THE SAME VOLUME IN SURGICAL PROCEDURES INVOLVING THE LOWER LIMBS- A PROSPECTIVE STUDY.

Student's Journal of Health Research Africa, 2023
Introduction: The emergence of levobupivacaine and ropivacaine has marked a new phase in advanced pain management techniques. This study aimed to create a comparative framework and assess the effects of epidural levobupivacaine and ropivacaine in ...
Ranjita Mohanty
doaj   +1 more source

Formation of pure two-electron triplet states in weakly coupled quantum dots attached to ferromagnetic leads

, 2006
Weakly coupled quantum dots in the Pauli spin blockade regime are considered with respect to spin-dependent transport. By attaching one half-metallic and one non-magnetic lead, the Pauli spin blockade if formed by a pure triplet state with spin moment ...
Fransson J, Inoshita T, J Fransson, Liu H W, Orgassa D   +4 more
core   +1 more source

TGFβ (transforming growth factor-β) blockade induces a human-like disease in a nondissecting mouse model of abdominal aortic aneurysm [PDF]

, 2017
Objective-Current experimental models of abdominal aortic aneurysm (AAA) do not accurately reproduce the major features of human AAA. We hypothesized that blockade of TGF beta (transforming growth factor-beta) activity-a guardian of vascular integrity ...
Clément, Marc, Esposito, Bruno, Finigan, Alison, Lareyre, Fabien, Mallat, Ziad, Master, Leanne, Patel, Meghana, Pohlod, Stefanie, Raffort, Juliette, Stergiopulos, Nikolaos, Taleb, Soraya, Trachet, Bram, Vandestienne, Marie   +12 more
core   +2 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Impact of Genetic Variation in Adrenergic Receptors on β-Blocker Effectiveness and Safety in Cardiovascular Disease Management: A Systematic Review

Pharmaceuticals
Background/Objectives: A systematic review was conducted to compile all the evidence on the impact of ADRB1 and ADRB2 genetic variants on the response to β-blockers, used for the management of cardiovascular diseases.
Houwaida Abbes, Paula Soria-Chacartegui, Asma Omezzine, Francisco Abad-Santos, Pablo Zubiaur   +4 more
doaj   +1 more source

Floquet-tailored Rydberg interactions

Nature Communications, 2023
The Rydberg blockade is a key ingredient for entangling atoms in arrays. However, it requires atoms to be spaced well within the blockade radius, which limits the range of local quantum gates.
Luheng Zhao, Michael Dao Kang Lee, Mohammad Mujahid Aliyu, Huanqian Loh   +3 more
doaj   +1 more source

Spin blockade in ground state resonance of a quantum dot

, 2002
We present measurements on spin blockade in a laterally integrated quantum dot. The dot is tuned into the regime of strong Coulomb blockade, confining ~ 50 electrons.
Blick, R. H., Eberl, K., Holleitner, A. W., Huettel, A. K., Kotthaus, J. P., Neumaier, K., Qin, H., Weinmann, D.   +7 more
core   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Coulomb "blockade" of Nuclear Spin Relaxation in Quantum Dots

, 2002
We study the mechanism of nuclear spin relaxation in quantum dots due to the electron exchange with 2D gas. We show that the nuclear spin relaxation rate is dramatically affected by the Coulomb blockade and can be controlled by gate voltage.
A. Abragam, B. L. Altshuler, D. Paget, D. V. Averin, D. V. Averin, I. L. Aleiner, I. D. Vagner, I. L. Aleiner, J. Korringa, L. D. Landau, M. I. Dyakonov, M. I. Dyakonov, P. W. Anderson, Y. B. Lyanda-Geller   +13 more
core   +1 more source