Results 161 to 170 of about 963,269 (378)
Циркумвентрикулярная система как «ворота» в головной мозг [PDF]
, 2013 Ціркумвентрікулярние органи (ЦВО), розташовані по периферії шлуночкової системи, відособлені серед інших структур головного мозку завдяки великій васкуляризацией і відсутністю типового гематоенцефалічного бар'єру.
Корсунская, Л.Л. +3 more
core
Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
Nature Reviews Neurology, 2018 Melanie D. Sweeney +2 more
semanticscholar +1 more source
Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy
Advanced Healthcare Materials, EarlyView.This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley +1 more source
Cell Communication and SignalingThe blood-brain barrier is a physiological protective barrier around blood vessels in the brain. It prevents most bacteria and harmful substances from entering the brain through the blood.
Yingying Quan +6 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.A novel dissolving microneedle platform preserves HPV virus‐like particle (VLP) immunogenicity by maintaining structural integrity, crucial for eliciting potent immune responses. Buccal administration induces robust immune response, high neutralizing antibody titers, and durable sterile protection across oral and vaginal mucosal sites.
Hyemi Kim +12 more
wiley +1 more source
Unveiling the hidden connection: the blood-brain barrier’s role in epilepsy
Frontiers in NeurologyEpilepsy is characterized by abnormal synchronous electrical activity of neurons in the brain. The blood-brain barrier, which is mainly composed of endothelial cells, pericytes, astrocytes and other cell types and is formed by connections between a ...
Jinkun Han +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail +3 more
wiley +1 more source
Group B Streptococci lyse endothelial cells to infect the brain in a zebrafish meningitis model.
PLoS BiologyTo cause meningitis, bacteria move from the bloodstream to the brain, crossing the endothelial cells of the blood-brain barrier. Most studies on how bacteria cross the blood-brain barrier have been performed in vitro using cultured endothelial cells, due
Sumedha Ravishankar +7 more
doaj +1 more source