Results 251 to 260 of about 4,387,004 (356)

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Multi-Omics Analysis of Human Blood Cells Reveals Unique Features of Age-Associated Type 2 CD8 Memory T Cells. [PDF]

Aging Cell
Matsui H, Cervantes M, Khalid MM, Tomusiak A, Dwaraka V, Landgrave-Gomez J, Kumaar PVA, Chen Q, Lasky-Su J, Stone J, Tiwari R, Kwok R, Ichikawa S, Ambrose BD, Riley RR, Hormazabal GV, Adkisson-Floro A, Alexandru AC, Smith R, Schilling B, Kasler HG, Verdin E.   +21 more
europepmc   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Safety and efficacy of allogeneic umbilical cord blood cells and erythropoietin combination therapy in patients with subacute stroke. [PDF]

Stem Cell Res Ther
Kim JM, Shin S, Lee D, Choi JI, Kwon HG, Hwang SSS, Cho SM, Kim YH, Lee J, Moon HI, Suh MR, Kim M.   +11 more
europepmc   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Microfluidic capillary transit velocity as a functional measure for sickle cell disease and in vitro-derived red blood cells.

Lab Chip
Oshabaheebwa S, Goreke U, Du Y, Wirth CL, Sekyonda Z, Benson BL, Fadaei P, Ley YB, Perez NM, Giannikopoulos P, Nguyen DN, Suster MA, Mohseni P, Gurkan UA.   +13 more
europepmc   +1 more source

Hypomorphic <i>ATP11c</i> is a novel regulator of decreased efficacy of transfused red blood cells in humans and mice. [PDF]

Hemasphere
Zimring JC, Hay AM, Dzieciatkowska M, Stephenson D, Haiman ZB, Kleinman S, Norris PJ, Busch MP, Roubinian N, Fermo E, Bianchi P, Keele GR, Page GP, D'Alessandro A.   +13 more
europepmc   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Red Blood Cells and Human Aging: Exploring Their Biomarker Potential. [PDF]

Diagnostics (Basel)
Kyriacou RP, Shibeeb S.
europepmc   +1 more source

Transplantation of human umbilical cord blood mesenchymal stem cells to treat a rat model of traumatic brain injury.

, 2012
Junjian Zhao, Naiyao Chen, Na Shen, Hui Zhao, Dali Wang, Junping Shi, Yang Wang, Xiufeng Cui, Zhenyu Yan, Hui Xue   +9 more
openalex   +2 more sources