Results 271 to 280 of about 4,387,004 (356)

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Bioenergetic signatures of circulating blood cells as biosensors of metabolic health in food-producing animals. [PDF]

Front Vet Sci
Ipharraguerre IR, Rosales Cavaglieri LA, Rimbach G.   +2 more
europepmc   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

Splenic accumulation of intact Plasmodium ovale sensu lato-infected red blood cells in a patient presenting with splenic rupture. [PDF]

PLoS Negl Trop Dis
Benabdelmoumen G, Itani O, Joste V, Houzé S, Hardy D, Bavozet F, Sylla M, Kho S, Anstey NM, Consigny PH, Sissoko A, Buffet P.   +11 more
europepmc   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Supercooled storage of red blood cells slows down the metabolic storage lesion. [PDF]

Sci Rep
Nemkov T, Isiksacan Z, William N, Senturk R, Boudreau LE, Yarmush ML, Acker JP, D'Alessandro A, Usta OB.   +8 more
europepmc   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Acquired BCL2 variants associated with venetoclax resistance in acute myeloid leukemia

Blood Advances
Fiona C. Brown, Xin Wang, Richard Birkinshaw, Chong Chyn Chua, Thomas Morley, Sila Kasapgil, Giovanna Pomilio, Piers Blombery, David C. S. Huang, Peter Czabotar, Salvatore F. Priore, Guang Yang, Martin Carroll, Andrew H. Wei, Alexander E. Perl   +14 more
doaj   +1 more source

Comparison of changes in blood cells and hemostatic biomarkers in mouse xenograft models of acute myeloid leukemia and acute promyelocytic leukemia. [PDF]

Res Pract Thromb Haemost
Archibald SJ, Sachetto ATA, Zhu X, Gangaraju R, Mackman N, Hisada Y.   +5 more
europepmc   +1 more source

Additional file 10 of Safety and efficacy of allogeneic umbilical cord blood cells and erythropoietin combination therapy in patients with subacute stroke

Jong Moon Kim, Seyoung Shin, Doyoung Lee, Jee In Choi, Hyeok Gyu Kwon, Sean S. S. Hwang, S.H. Cho, Yun-Hee Kim, J. E. Lee, Hyun Im Moon, Mi Ri Suh, Minyoung Kim   +11 more
openalex   +1 more source