Results 111 to 120 of about 659,716 (258)

Effect of Different Magnetite Nanoparticle Coatings on Blood Circulation, Biodistribution, Tumor Accumulation and Penetration. [PDF]

Pharmaceutics
Mochalova EN, Yurchenko MA, Vorobeva TS, Maedi DA, Chernov NO, Kolesnikova OA, Tereshina ED, Shipunova VO, Yakovtseva MN, Nikitin PI, Nikitin MP.   +10 more
europepmc   +1 more source

Engineering of Glioblastoma‐Derived Biomimetic Vesicles and Their Structural and Molecular Features

Advanced Healthcare Materials, EarlyView.
ABSTRACT Biomimetic nanosystems and vesicles have arisen as a novel approach to design vesicular transport systems with diverse therapeutic potential. The ‘biomimetic’ strategy involves the integration of cell membrane components into lipid bilayers, conferring them with biological properties originating from the cell of origin. Until now, most studies
Noelia Hernández‐Lobato, Hanan Abumanhal‐Masarweh, Martí de Cabo, Pablo Guerra, Marilena Hadjidemetriou, Neus Lozano, Kostas Kostarelos   +6 more
wiley   +1 more source

Effects of Temporary Interruption of Hepatic Blood Circulation on the Liver, Brain, and Heart During Experimental Cholestasis. [PDF]

Cureus
Kimadze K, Turmanidze T, Jandieri K, Jandieri L, Ramishivili M, Benashvili L, Otarashvili R, Asatiani E, Kikalishvili L.   +8 more
europepmc   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source

A soft biosensor with printable responsive hydrogel interfaces for detection and differentiation of blood circulation complications. [PDF]

Natl Sci Rev
Qiu Y, Yang G, Wang Z, Pang B, Zhou S, Zheng Q, Bu T, Tian J, Xue B, Lee J, Choi Y, Yin Z, Wu C, Liu Y, Wu H.   +14 more
europepmc   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Multiscale modeling of blood circulation with cerebral autoregulation and network pathway analysis for hemodynamic redistribution in the vascular network with anatomical variations and stenosis conditions. [PDF]

PLoS Comput Biol
Liu J, Kanoke A, Endo H, Niizuma K, Suito H.   +4 more
europepmc   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

The Effects of Temporary Interruption of Hepatic Blood Circulation. [PDF]

Cureus
Turmanidze T, Jandieri K, Jandieri L, Benashvili L, Otarashvili R, Asatiani E, Sulaberidze G, Gorgadze G, Kikalishvili L.   +8 more
europepmc   +1 more source