Results 71 to 80 of about 6,572,687 (353)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The Aging Male, 2023 Background Erectile dysfunction (ED) is a common diabetes-related complication.Materials and methods This study examined the effect of daily low-dose tadalafil (5 mg) on patients’ quality of life (including that of sex life) and blood circulation ...
Jong Seung Lee +7 more
doaj +1 more source
Rapid clearance of Borrelia burgdorferi from the blood circulation
Parasites & Vectors, 2020 Borrelia burgdorferi is a tick-borne spirochete that causes Lyme borreliosis (LB). After an initial tick bite, it spreads from the deposition site in the dermis to distant tissues of the host.
L. Liang +6 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Circulating trophoblast in maternal blood
Prenatal Diagnosis, 2003 AbstractThis review describes the status of circulating trophoblast, but is considered in the perspective that only a specific subset of trophoblast cells circulates in the maternal blood. The consequences for isolation, identification and clinical potential are described. Copyright © 2003 John Wiley & Sons, Ltd.
Oudejans, Cees B M +5 more
openaire +4 more sources
Nano-Micro Letters, 2019 HighlightsManganese-zeolitic imidazolate frameworks (Mn-ZIF-90) with both high drug loading and magnetic resonance imaging (MRI) in vitro and in vivo were prepared.The modification of a newly designed pH-protective and active-targeting Y1 receptor ligand
Zhenqi Jiang +12 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
LES of non-Newtonian physiological blood flow in a model of arterial stenosis [PDF]
, 2012 Large Eddy Simulation (LES) is performed to study the physiological pulsatile transition-to-turbulent non-Newtonian blood flow through a 3D model of arterial stenosis by using five different blood viscosity models: (i) Power-law, (ii) Carreau, (iii ...
Ahmed +31 more
core +1 more source
European journal of pharmaceutics and biopharmaceutics, 2019 Retinal pigment epithelium (RPE) is a major part of blood-retinal barrier that affects drug elimination from the vitreous to the blood and drug distribution from blood circulation into the eye.
Eva Ramsay +8 more
semanticscholar +1 more source