Results 81 to 90 of about 6,572,687 (353)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Hemorrhagic Shock and Stress - Cause and Consequence of Hemorheology Disturbances on the Example of the Changes in Erythrocyte Aggregation [PDF]
Journal of Stress Physiology & Biochemistry, 2014 Stress, being the general reaction of the organism to the physical and psychological effects, accompanies all the stages of somatic and psychic formation. Hemorrhagic shock occurring at blood loss appears to be a powerful stress for the organism.
Mantskava M.M. +3 more
doaj
Blood Circulation-Prolonging Peptides for Engineered Nanoparticles Identified via Phage Display.
Nano letters (Print), 2019 Sustaining blood retention for theranostic nanoparticles is a big challenge. Various approaches have been attempted and have demonstrated some success but limitations remain.
Pei-pei Jin +14 more
semanticscholar +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Quantification of Bronchial Circulation Perfusion in Rats [PDF]
, 2004 The bronchial circulation is thought to be the primary blood supply for pulmonary carcinomas. Thus, we have developed a method for imaging and quantifying changes in perfusion in the rat lung due to development of the bronchial circulation.
Clough, Anne V. +5 more
core +1 more source
Murray's law revisited: Qu\'emada's fluid model and fractal trees [PDF]
, 2015 In 1926, Murray proposed the first law for the optimal design of blood vessels. He minimized the power dissipation arising from the trade-off between fluid circulation and blood maintenance.
Mauroy, Benjamin, Moreau, Baptiste
core +5 more sources
ACS Nano, 2018 Research into long-circulating nanoparticles has in the past focused on reducing their clearance by macrophages. By engineering a hierarchical polyethylene glycol (PEG) structure on nanoparticle surfaces, we revealed an alternative mechanism to enhance ...
Hao Zhou +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Does Hydration Impact Memory: A Systematic Review [PDF]
, 2018 With 60% of the adult human body composed of water it makes sense that maintaining proper hydration levels is important to survival as well as living a healthy life. Water has many roles throughout the human body: thermoregulation, being a carrier, being
Ellis-Lepard, Kelsey
core +2 more sources