Results 51 to 60 of about 4,602,840 (385)

Shear viscosity and nonlinear behaviour of whole blood under large amplitude oscillatory shear [PDF]

, 2013
We investigated experimentally the rheological behavior of whole human blood subjected to large amplitude oscillatory shear under strain control to assess its nonlinear viscoelastic response.
Alves, M.A., Carneiro, J., Cerejo, A., Oliveira, Monica, Pinho, F.T., Sousa, P.C., Vaz, R.   +6 more
core   +1 more source

The Endocannabinoid System: A Potential Therapeutic Target for Coagulopathies

Metabolites, 2022
Abnormal blood coagulation or coagulopathy is a common manifestation of many pathological conditions. It occurs when there is an imbalance between the activities of the coagulation system and the fibrinolytic system, leading to excessive or impaired ...
Wujood Khayat, Christian Lehmann
doaj   +1 more source

Viscoelastic coagulation test for liver transplantation [PDF]

Anesthesia and Pain Medicine, 2020
Coagulation and transfusion management in patients undergoing liver transplantation is challenging. Proper perioperative monitoring of hemostasis is essential to predict the risk of bleeding during surgery, to detect potential causes of hemorrhage in ...
Sun Young Park
doaj   +1 more source

Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

Nature Communications, 2016
Aberrant immune responses represent the underlying cause of central nervous system (CNS) autoimmunity, including multiple sclerosis (MS). Recent evidence implicated the crosstalk between coagulation and immunity in CNS autoimmunity.
K. Göbel, Susann Pankratz, Chloi-Magdalini Asaridou, A. Herrmann, S. Bittner, M. Merker, T. Ruck, Sarah Glumm, F. Langhauser, P. Kraft, Thorsten F. Krug, J. Breuer, M. Herold, C. Gross, D. Beckmann, A. Korb-Pap, Michael K. Schuhmann, S. Kuerten, I. Mitroulis, C. Ruppert, M. Nolte, C. Panousis, L. Klotz, B. Kehrel, T. Korn, H. Langer, T. Pap, B. Nieswandt, H. Wiendl, T. Chavakis, C. Kleinschnitz, S. Meuth   +31 more
semanticscholar   +1 more source

Procoagulant Activity of Blood and Microvesicles Is Disturbed by Pneumococcal Pneumolysin, Which Interacts with Coagulation Factors

Journal of Innate Immunity, 2022
The coagulation and contact systems are parts of the innate immune system as they prevent bleeding and dissemination of pathogens and also contribute to microbial killing by inflammatory reactions and the release of antimicrobial peptides.
Sonja Oehmcke-Hecht, Claudia Maletzki, Surabhi Surabhi, Nikolai Siemens, Valeria Khaimov, Lisa Marie John, Sina Mariella Peter, Sven Hammerschmidt, Bernd Kreikemeyer   +8 more
doaj   +1 more source

Silica Nanoparticles Effects on Blood Coagulation Proteins and Platelets

Biochemistry Research International, 2016
Interaction of nanoparticles with the blood coagulation is important prior to their using as the drug carriers or therapeutic agents. The aim of present work was studying of the primary effects of silica nanoparticles (SiNPs) on haemostasis in vitro.
V. Gryshchuk, N. Galagan
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Platelet Biochemistry and Morphology after Cryopreservation [PDF]

, 2020
Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle, Feys, Hendrik, Six, Katrijn   +2 more
core   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Alterations of blood coagulation in controlled human malaria infection

Malaria Journal, 2016
Alterations of blood coagulation are thought to be involved in malaria pathogenesis. This study had the aim to investigate changes of blood coagulation under the standardized conditions of controlled human malaria infection.
J. Riedl, B. Mordmüller, S. Koder, I. Pabinger, P. Kremsner, S. Hoffman, M. Ramharter, C. Ay   +7 more
semanticscholar   +1 more source