Results 71 to 80 of about 4,602,840 (385)

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Patient perspective on living with mild hemophilia in Germany: results from a nationwide survey

Frontiers in Medicine
IntroductionThe disease burden and bleeding risk of patients with mild hemophilia may be underestimated. Their health-related quality of life (QoL) may be negatively impacted by insufficient treatment and bleed-related joint damage connected to a ...
Rosa Sonja Alesci, Georg Goldmann, Susan Halimeh, Katharina Holstein, Christoph Königs, Wolfgang Miesbach, Christian Pfrepper, Martin Olivieri   +7 more
doaj   +1 more source

Hydrodynamical activation of blood coagulation in stenosed vessels. Theoretical analysis [PDF]

Компьютерные исследования и моделирование, 2012
The mechanisms of hydrodynamical activation of blood coagulation system are investigated in stenosed vessels for a wide range of Reynolds number values (from 10 up to 500).
Aleksey Sergeevich Rukhlenko, Ksenia Evgenyevna Zlobina, Georgy Theodorovich Guria   +2 more
doaj   +1 more source

Development of an Optical Method for the Evaluation of Whole Blood Coagulation

Biosensors, 2021
Blood coagulation is a defense mechanism, which is activated in case of blood loss, due to vessel damage, or other injury. Pathological cases arise from malfunctions of the blood coagulation mechanism, and rapid growth of clots results in partially or ...
Marinos Louka, Efstathios Kaliviotis
doaj   +1 more source

ON THE COAGULATION OF BLOOD

Quarterly Journal of Experimental Physiology, 1913
Oxalate plasma, when prepared with certain precautions and filtered through a Berkefeld filter, does not clot on the addition of calcium chloride.An investigation of this fact has led to the following conclusions:—Plasma separated from the corpuscular elements in the ordinary way by centrifugalisation at a moderate speed still contains some blood ...
Harold Pringle, W. Cramer
openaire   +2 more sources

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

EPCR-dependent PAR2 activation by the blood coagulation initiation complex regulates LPS-triggered interferon responses in mice.

Blood, 2015
Infection and inflammation are invariably associated with activation of the blood coagulation mechanism, secondary to the inflammation-induced expression of the coagulation initiator tissue factor (TF) on innate immune cells. By investigating the role of
H. P. Liang, E. Kerschen, I. Hernandez, Sreemanti Basu, M. Zogg, F. Botros, S. Jia, M. Hessner, J. Griffin, W. Ruf, H. Weiler   +10 more
semanticscholar   +1 more source

Molar substitution and C2/C6 ratio of hydroxyethyl starch: influence on blood coagulation [PDF]

, 2017
Background. Development of hydroxyethyl starches (HES) with a low impact on blood coagulation but a long intravascular persistence is of clinical interest.
Bombeli, T., Burmeister, M.-A, Fisch, A., Frascarolo, P., Madjdpour, C., Schramm, S., Spahn, D. R., von Roten, I.   +7 more
core  

Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro, Manuela Dicarlo, Chiara Zecca, Daniele Urso, Maria Teresa Dell'Abate, Davide Vilella, Francesco Borlizzi, Roberta Zerlotin, Angela Oranger, Graziana Colaianni, Silvia Colucci, Maria Grano, Giancarlo Logroscino   +12 more
wiley   +1 more source

Blood Coagulation Testing Smartphone Platform Using Quartz Crystal Microbalance Dissipation Method

Sensors, 2018
Blood coagulation function monitoring is important for people who are receiving anticoagulation treatment and a portable device is needed by these patients for blood coagulation self-testing. In this paper, a novel smartphone based blood coagulation test
Jia Yao, Bin Feng, Zhiqi Zhang, Chuanyu Li, Wei Zhang, Zhen Guo, Heming Zhao, Lianqun Zhou   +7 more
doaj   +1 more source