Results 81 to 90 of about 264,190 (272)

Nanoscale Biodegradable Printing for Designed Tuneability of Vaccine Delivery Kinetics

Advanced Materials, EarlyView.
Spatiotemporal Controlled Release Inks of Biocompatible polyEsters (SCRIBE) is a novel 2PP resin family with sub‐micron resolution and tuneable hydrolysis. SCRIBE enables direct printing of hollow microparticles with complex chemistries and geometries inaccessible to molding techniques, which are used to modulate antibody titers and class switching as ...
David J. Peeler, Rujie Sun, Ceren Kütahya, Patrick Peschke, Kun Zhou, Giulia Brachi, Jonathan Yeow, Omar Rifaie‐Graham, Jonathan P. Wojciechowski, Thomas F. F. Fernandez Debets, Vernon LaLone, Xin Song, Krunal Polra, Paul F. McKay, John S. Tregoning, Robin J. Shattock, Molly M. Stevens   +16 more
wiley   +1 more source

Surface-dependent Coagulation Enzymes: Flow Kinetics of Factor Xa Generation on Live Membranes [PDF]

J. Biological Chemistry, 276, (2001), 7827-7835, 2001
The initial surface reactions of the extrinsic coagulation pathway on live cell membranes were examined under flow conditions. Generation of fXa (activated coagulation factor X) was measured on spherical monolayers of epithelial cells with a total surface area of 41-47 cm$^{2}$ expressing TF(tissue factor) at $>25$ fmol/cm$^{2}$.
arxiv  

A finite element / neural network framework for modeling suspensions of non-spherical particles. Concepts and medical applications [PDF]

arXiv, 2020
An accurate prediction of the translational and rotational motion of particles suspended in a fluid is only possible if a complete set of correlations for the force coefficients of fluid-particle interaction is known. The present study is thus devoted to the derivation and validation of a new framework to determine the drag, lift, rotational and ...
arxiv  

A Library of Polyphenol‐Amino Acid Condensates for High‐Throughput Continuous Flow Production of Nanomedicines with Ultra‐High Drug Loading

Advanced Materials, EarlyView.
A scalable and flexible library of natural, renewable tea polyphenol, and amino acid condensate colloidal spheres, synthesized via a one‐step process, facilitates the preparation of ultra‐high drug‐loading nanomedicines with precise size control and uniform dispersion using continuous‐flow microfluidics.
Zeng Yi, Xiaomin Ma, Qiulan Tong, Lei Ma, Yunfei Tan, Danni Liu, Chaoliang Tan, Junze Chen, Xudong Li   +8 more
wiley   +1 more source

Threadlike bundle of tubules running inside blood vessels: New anatomical structure [PDF]

arXiv, 2002
According to current anatomy, the arteries and veins do not have threadlike structures running inside the vessels. Despite such prevailing knowledge here we report on observation of a novel structure inside the blood vessels of rats and rabbits, which is a semi-transparent elastic bundle of tubules whose diameters are of 10$\mu$m order.
arxiv  

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

Integrating musculoskeletal ultrasound as a shared decision-making tool in hemophilia care: observations from a 3-year study

Research and Practice in Thrombosis and Haemostasis
Background: Hemophilia significantly impacts joint health, necessitating innovative strategies for early detection and management of joint damage. Objectives: This study assessed the impact of incorporating musculoskeletal ultrasound (MSKUS) into shared ...
Azusa Nagao, Satoko Orita, Katsuyuki Fukutake, Hideyuki Takedani   +3 more
doaj  

THE PARALLEL EFFECTS OF MAGNESIUM ON THE COMPLEMENTARY AND COAGULATIVE ACTIVITIES OF BLOOD SERUM [PDF]

, 1949
Frank Maltaner, José Oliveira de Almeida   +1 more
openalex   +1 more source

An Anticoagulant Coating Based on a Block Phosphocholine Copolymer for Potential Applications in Blood Contact Devices

Advanced Materials Interfaces, EarlyView.
Anticoagulant properties are critical for blood‐compatible materials, and anticoagulant coatings are a common key issue for blood‐contacting medical devices. In this study, a block copolymer poly(2‐methacrylenoxyethyl phosphocholine‐b‐glycidyl) (PMPC‐b‐GMA) is synthesized, using reversible addition‐fragmentation chain transfer polymerization (RAFT) and
Xinli Lu, Yahong Kang, Xuebin Wang, Weijie Wang, Changsheng Liu, Hongyan Jiang, Yuan Yuan   +6 more
wiley   +1 more source

Nanostructured 316L Stainless Steel Stent Surfaces Improve Corrosion Resistance, and Enhance Endothelization and Hemocompatibility

Advanced Materials Interfaces, EarlyView.
This study investigates the impact of nanostructured surface modification on corrosion resistance, HUVEC functions, and platelet interactions of 316L SS for cardiovascular stents. Nanostructured surfaces enhanced HUVEC proliferation, migration, and angiogenesis‐related gene expression while reducing platelet adhesion and hemolysis.
Yasar Kemal Erdogan, Pelin Mutlu, Batur Ercan   +2 more
wiley   +1 more source