Results 131 to 140 of about 186,764 (349)

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

open access: yesAdvanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang   +11 more
wiley   +1 more source

Correction to: New clotting disorders that cast new light on blood coagulation and may play a role in clinical practice [PDF]

open access: bronze, 2018
A Girolami   +4 more
openalex   +1 more source

Mechanical Force Storage and Reprogramming Hydrogel for Scarless Repair of Sports Joint Wounds

open access: yesAdvanced Science, EarlyView.
Inspired by the energy conversion of tendons, the “energy transit station” hydrogel is designed. The hydrogel not only shields stress concentration in sports injuries, but also reprograms energy forms to provide reasonable biomimetic contraction for wounds.
Jiakang Zhang   +10 more
wiley   +1 more source

Cyclosporine treatment of acquired hemophilia due to factor VIII antibodies [PDF]

open access: yes, 2000
Acquired hemophilia, caused by autoantibodies against coagulation factor VIII, is usually treated with steroids, cyclophosphamide, intravenous gammaglobulins and sporadically other drugs.
Baele, Gaston   +2 more
core  

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

open access: yesAdvanced Science, EarlyView.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen   +11 more
wiley   +1 more source

Concizumab prophylaxis in persons with hemophilia A or B with inhibitors: patient-reported outcome results from the phase 3 explorer7 study

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: Patient-reported outcomes (PROs) reflect patient perceptions of disease and treatment and are important for evaluating new therapies. Objectives: Evaluate the effects of once-daily concizumab prophylaxis on health-related quality of life ...
Huyen Tran   +12 more
doaj   +1 more source

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

open access: yesAdvanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu   +15 more
wiley   +1 more source

THYROID HORMONES INFLUENCE ON PRIMARY HAEMOSTASIS STATUS AND CERTAIN ENZYME SYSTEMS IN LOCAL FORMS OF PERITONITIS [PDF]

open access: yes, 2017
One of the main significances in postoperative changes in biochemical and enzymes criterion of the pathology of the organs depends to T-3, the decreasing of level of which in blood plasma is related to disorders in peripheral T-4 monoiodising and depends
Grodetskyi, V.K.   +5 more
core  

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