Results 11 to 20 of about 92,320 (231)
Alterations of Blood Coagulation in Patients with Pancreatic Disorders [PDF]
Hemorrhage as uell as thromboembolism is often found in patients uith pancreatic diseases. Ide systematically examined in the past tuo years blood coagulation factors in Ikpatients, uho uere admitted to our clinic uith elevated levels of amylases or uho were transfered from other hospitals after complications had occured.5B patients uith increased ...
H. Kästering+3 more
openalex +2 more sources
Quality of life in children and adolescents with blood coagulation disorders and hemoglobinopathies. [PDF]
Silva LTD+8 more
europepmc +2 more sources
Modeling Disorders of Blood Coagulation in the Zebrafish [PDF]
Hemostasis, the process of blood clot formation and resolution in response to vascular injury, and thrombosis, the dysregulation of hemostasis leading to pathological clot formation, are widely studied. However, the genetic variability in hemostatic and thrombotic disorders is incompletely understood, suggesting that novel mediators have yet to be ...
Colin A. Kretz+2 more
openaire +3 more sources
Inherited disorders of blood coagulation
Hemostasis is traditionally defined as a physiological response to blood vessel injury and bleeding, which entails a co-ordinated process involving the blood vessel, platelets, and blood clotting proteins (i.e. coagulation factors). Hemostasis can be divided into primary and secondary components.
LIPPI, Giuseppe+3 more
openaire +3 more sources
The EHA Research Roadmap: Blood Coagulation and Hemostatic Disorders
In 2016, the European Hematology Association (EHA) published the EHA Roadmap for European Hematology Research1 aiming to highlight achievements in the diagnostics and treatment of blood disorders, and to better inform European policy makers and other stakeholders about the urgent clinical and scientific needs and priorities in the field of hematology ...
David-Alexandre Trégouët+14 more
openaire +7 more sources
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Peculiarities of blood coagulation disorders in patients with COVID-19
Aim. To study the relationship of hemostatic disorders with inflammation and estimate their role in the course and outcomes of COVID-19. Materials and methods. We examined 215 consecutive patients with moderate and severe forms of acute COVID-19. The patients were on anticoagulants and immunosuppressive drugs.
Natalia G. Evtugina+9 more
openaire +4 more sources
Liver‐specific lncRNAs associated with liver cancers
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina+3 more
wiley +1 more source
Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia
ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro+12 more
wiley +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source